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Type AB with Uterine Fibroids


I am a 48 year old female with Type AB blood. I have a strong family history of uterine fibroids for several generations. Many relatives had hysterectomies. I do not want to go this course. I see very little written about this common pre-menopausal problem in women. Any advice? I am a month into the diet. My periods are heavy and painful.


Uterine fibroids (benign tumors of the uterus, typically non-symptomatic unless embedded in the lining when they can cause heavy bleeding at menses) are more common in blood groups A and AB, probably due to the fact that cellular growth factors that are responsible for the proliferation of uterine tissue can be stimulated by the type A antigen.(1) It has also been shown that hyperlastic (rapidly growing) endometrial tissue is heavily infiltrated with blood group antigens, whereas normal endometrial tissue is not. (2)

Typically, the AB works well in lowering growth-stimulating polyamines, which can accelerate cellular turnover, especially by the use of soy products.

Two herbal remedies traditionally used for treating uterine fibroids are Capsella or Shepherd's Purse (3) and chlorophyll (the green pigment in plants). Capsella may have as its basis of action the fact that it is rich in fumaric acid (4) which is known to inhibit excessive cellular turnover.

As with any medical condition characterized by excess bleeding, it is prudent to make sure that the cause of the bleeding is indeed not from more serious reasons. As such one should always bring such occurances to the attention of one's gyneocologist or primary care phsyician.

1. Berchuck A, Soisson AP, Soper JT, Clarke-Pearson DL, Bast RC Jr, McCarty KS Jr. Reactivity of epidermal growth factor receptor monoclonal antibodies with human uterine tissues. Arch Pathol Lab Med. 1989 Oct;113(10):1155-8.

2.Tanaka K, Yasuda M, Motizuki M, Sasaki T, Yamazaki T, Kurose T, Sasagawa M, Hando T, Ohmori M. [Diagnosis and treatment of endometrial hyperplasia]. Gan To Kagaku Ryoho. 1989 Apr;16(4 Pt 2-3):1598-604.

3. Shipochliev T. [Uterotonic action of extracts from a group of medicinal plants]. Vet Med Nauki. 1981;18(4):94-8.

4. Kuroda K, Akao M. Antitumor and anti-intoxication activities of fumaric acid in cultured cells. Gann. 1981 Oct;72(5):777-82.

The Ask Dr. D'Adamo internet advice column ran from 1996 to 2009, at which time Dr. D'Adamo's teaching and programming responsibilities no longer allowed him to devote time and resources to directly answering visitor questions. However we've recently reorganized this treasure-trove of material and made it again available to his readership. He occasionally posts new entries. These are marked with a NEW tag.

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