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Slowly, They Are Catching On


STUDY:
Carbohydrate expression in the intestinal mucosa.

JOURNAL:
Adv Anat Embryol Cell Biol 2001;160:III-IX, 1-91

AUTHORS:
Sharma R, Schumacher U.

ABSTRACT:
A study of gut-associated lymphoid tissue (GALT) was undertaken to test the hypothesis that lymphocyte-epithelial interactions influence the glycosylation of cells overlying Peyer's patches. The effects of diet and microbial flora were analysed by comparing the data from male Wistar germ-free rats, with conventional or human flora. CONCLUSIONS: (1) the interactions between diet and flora alter the mucosal architecture and the activity of endocrine cells; (2) the dietary changes are influential in modifying the epithelial mucin predominantly in the small intestine while the microbial flora influences the mucosal architecture predominantly in the large intestine.



COMMENTARY:
This article supports the contentions I have written on for the last 15 years:

1.The health of the gut directly parallels the health of the immune system.

2.Diet influences the health of the mucus lining of the gut, which in itself is under the influence of ABO blood group and secretor status.

3. The health of the gut mucus influences the composition and quality of the intestinal flora, which is again also under the influence of ABO blood group.









The Ask Dr. D'Adamo internet advice column ran from 1996 to 2009, at which time Dr. D'Adamo's teaching and programming responsibilities no longer allowed him to devote time and resources to directly answering visitor questions. However we've recently reorganized this treasure-trove of material and made it again available to his readership. He occasionally posts new entries. These are marked with a NEW tag.



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