Nucleotide

Genomics

See Also

• Base pair
• Chromosome?
• DNA?
• Gene?
• RNA
• [Single nucleotide polymorphisms (SNPs)]?

Description

A nucleotide is a chemical compound that consists of a heterocyclic base, a sugar, and one or more phosphate groups. In the most common nucleotides the base is a derivative of [Purine? purine] or pyrimidine, and the sugar is the pentose (five-carbon sugar) deoxyribose or ribose.

Structure of a nucleotide

Nucleotides are the structural units of RNA, DNA?, and several cofactors - CoA, FAD, FMN, NAD, and NADP. In the cell they play important roles in energy production, metabolism, and signaling.

Nomenclature

Nucleotide names are abbreviated into standard three- or four-letter codes. The first letter is lower case and indicates whether the Nucleotide in question is a deoxyribonucleotide (denoted by a d) or a ribonucleotide (no letter). The second letter indicates the nucleoside corresponding to the nucleobase:

G: Guanine

A: Adenine?

T: Thymine?

C: Cytosine?

U: Uracil not present in DNA, but takes the place of Thymine in RNA

The third and fourth letters indicate the length of the attached phosphate chain (Mono-, Di-, Tri-) and the presence of a phosphate (P).

For example, deoxy-cytidine-triphosphate is abbreviated as dCTP.

Links

• Nucleotide Metabolism
• Entrez Nucleotide
• Nuelcotide Page from Reactome.org

Attribution

• This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article "Nucleotide".