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Aberrent glycosylation in malignant and pre-malignant states
[[Glycomics]] ====See Also==== * [['A-Like' tumor antigens]] * [[Thomsen-Friedenreich (T-Tn) antigen]] . . . their [[Gene|genes]] in defining cancer cell [[Phenotype|phenotypes]]. Glycosylation appears to be . . .
7K - last updated 2006-06-04 05:43 UTC by AlanGoldenberg
Allele
[[Genomics]] ====See Also==== * [[Allele]] * [[Chromosome]] * [[DNA]] * [[Genotype]] * [[Genetic architecture]] . . . * [[Genetic linkage]] * [[Locus]] * [[Phenotype]] ====Description==== One of the variant . . . of the gene is said to be [[heterozygous]]. [[Phenotype]]s (the expressed characteristics) associated . . . but often they are neither. A dominant phenotype will be expressed when only one allele of . . . associated type is present, whereas a recessive phenotype will only be expressed when both alleles . . .
5K - last updated 2006-05-27 14:57 UTC by TomGreenfield
Allergy, ABO Blood Group and Secretor Status
[[Pathology]] ====See Also==== * [[Allergens, Dietary]] * [[Allergy]] * [[Atopy]] * [[Basophils and Mast . . . asthma was significantly related to nonsecretor phenotype (especially if they were blood type O) for . . .
7K - last updated 2006-06-02 07:22 UTC by AlanGoldenberg
Alpha 1-antitrypsin (A1AT)
[[Physiology]] ====See Also==== * [[Serum pepsinogen levels and ABO blood groups]] (one study reports . . . aspects of alpha(1)-antitrypsin deficiency: phenotypes and genetic modifiers of emphysema risk". . . .
4K - last updated 2006-05-27 14:58 UTC by TomGreenfield
Amorph
[[Genomics]] ====See Also==== * [[Genotype]] * [[Phenotype]] * [[Mutation]] * [[Single nucleotide polymorphisms . . . and therefore the gene is expressed [[Phenotype|phenotypically]] as the lack of any [[Antigen, . . .
2K - last updated 2006-05-27 12:34 UTC by PeterDAdamo
Antigen, ABH
[[Immunology]] ====See Also==== * [[Blood group antigen proteins (chart)]] * [[Antigen]] * [[ABO Antibodies]] . . . H substance is produced by secretors of all ABH phenotypes, but much less A substance, and virtually . . . first serologically, as they exhibited unique phenotypes under defined conditions; also by characteristic . . .
21K - last updated 2006-06-30 16:34 UTC by PeterDAdamo
Aquired B Phenotype
[[Immunology]] ====Description==== Acquired B state should be considered when the serum of a patient . . . group AB with a weak B antigen. The acquired B phenotype arises through the modification of the A . . . antibodies, do not react with the acquired B phenotype - Such information may be carried in the . . .
2K - last updated 2006-04-19 20:35 UTC by ool-435621f6.dyn.optonline.net
Association analysis of common variants of STAT6, GATA3, and STAT4 to asthma and high serum IgE phenotypes.
[[References]] ====Association analysis of common variants of STAT6, GATA3, and STAT4 to asthma and high . . . serum IgE phenotypes.==== J Allergy Clin Immunol. 2005 Jan;115(1):80-7. . . . with different asthma and atopy related phenotypes among both the family and case-control data . . . showed an initial association to asthma-related phenotypes. Elucidation of the importance of the identified . . .
2K - last updated 2006-05-12 09:23 UTC by PeterDAdamo
Association between secretor status and respiratory viral illness
[[References]] ====Association between secretor status and respiratory viral illness==== Raza MW, Blackwell . . . to identify Lewis (Le) blood group antigen phenotypes (Le(a) non-secretor; Le(b) secretor). SUBJECTS--Patients . . . testing, proportions of Le(a), Le(b), and Le- phenotypes in 872 samples of nasal washings from a . . .
2K - last updated 2006-05-04 22:57 UTC by PeterDAdamo
Associations between atopic diseases and the polymorphic systems ABO, Kidd, Inv and red cell acid phosphatase
[[References]] ====Associations between atopic diseases and the polymorphic systems ABO, Kidd, Inv and . . . bronchial asthma, and acute urticaria) the phenotype and gene distribution of 15 genetic blood . . . that there are also associations between the phenotypes Jk (a-b+), Inv(1) and red cell acid phosphatase . . .
2K - last updated 2006-05-12 10:16 UTC by PeterDAdamo
Biometrics and biostatistics
[[Anthropometry]] ====See Also==== * [[Auxology]] ====Description==== Biostatistics or biometry is the . . . link variation in genotype with a variation in phenotype. This has been used in agriculture to improve . . .
2K - last updated 2006-05-06 10:27 UTC by PeterDAdamo
Blood Groups and Anthropology
[[Paleoserology]] ====Attribution==== Excerpted from the Complete Blood Type Encyclopedia by Peter D'Adamo, . . . Menarcheal age in relation to ABO blood group phenotypes and haemoglobin-E genotypes. J Assoc Physicians . . .
48K - last updated 2006-05-26 06:48 UTC by AlanGoldenberg
Celiac Disease (Sprue), ABO and Secretor Blood Types
[[Pathology]] ====See Also==== * [[The C282Y mutation may have been positively selected as it mitigates . . . especially true for the recessive Lewis (a-b-) [[phenotype]]. Evidence suggests an increased prevalence . . . negative Lewis celiac patients. (9) ====Lewis phenotype, secretor status, and coeliac disease.==== . . . disease using red cell Lewis (Le) blood group [[phenotype]] to infer secretor status. Among 73 patients . . . 1. Dickey W, Wylie JD, Collins JS, et al. Lewis phenotype, secretor status, and coeliac disease. Gut . . .
9K - last updated 2007-01-19 21:51 UTC by DonStJohn
Cholesterol and triglyceride levels, ABO blood groups and secretor status
[[Lipidomics]] ====See Also==== * [[Endothelial dysfunction]] * [[Cardiovascular disease, ABO blood groups . . . study of the association between ABO phenotype and total serum cholesterol level in a Japanese . . . Japan. * The relationship between ABO blood phenotype and total serum cholesterol (TC) level was . . . whether an elevated TC level is associated with phenotype A, as has been demonstrated in many West . . . are elevated on average by about 4 mg/dl in phenotype A compared to non-A in the Japanese (P < . . .
19K - last updated 2006-07-04 11:42 UTC by PeterDAdamo
Copy number polymorphisms
[[Genomics]] ====See Also==== * [[DNA]] * [[Polymorphism]] * [[Single nucleotide polymorphisms (SNPs)]] . . . to the idea that you could get clinical phenotype related to just gene dosage, not having an . . .
3K - last updated 2006-07-06 10:59 UTC by PeterDAdamo
Data Center
====Somatotyping and ABO Blood Groups==== =====See Also==== * [[Somatotype]] =====Data: Comparison of . . . II Outcomes==== =====See Also==== * [[Acetylator phenotype]] * [[Phase II metabolism]] * [[Phase I metabolism]] . . .
2K - last updated 2006-06-07 01:04 UTC by PeterDAdamo
Deoxyribonucleic acid (DNA)
[[Genomics]] ====See Also==== * [[Allele]] * [[Base pair]] * [[Chromosome]] * [[Genetic architecture]] . . . * [[Locus]] * [[Mutation]] * [[Nucleotide]] * [[Phenotype]] * [[RNA (ribonucleic acid)]] * [[Transcription . . .
10K - last updated 2006-07-06 11:22 UTC by PeterDAdamo
Distribution of M and N blood groups
[[Paleoserology]] ====See Also==== * [[MNS Blood Group]] ====Description==== The M and N [[Allelomorph|allelomorphs]] . . . <tr><td>MM . . .
6K - last updated 2006-05-17 09:23 UTC by TomGreenfield
Duffy blood group system
[[Polymorphism]] ====See Also==== * [[Allele]] * [[Chemokines]] * [[Interleukin-8 (IL-8)]] FY Gene locus . . . times. Using these antibodies three common [[Phenotype|phenotypes]] were defined: Fy(a+b+), Fy(a+b-), . . . the majority of Blacks had the [[erythrocyte]] phenotype Fy(a-b-). This phenotype is exceedingly rare . . . in Whites. The frequency of the Fy(a-b-) phenotype is 68 percent in American Blacks and 88-100 . . . The molecular basis for the Fy(c-b-) phenotype is the result of a point mutation in the . . .
15K - last updated 2006-05-14 19:52 UTC by PeterDAdamo
FOXP2 (forkhead box P2)
[[Linguistics]] ====See Also==== * [[FOX proteins]] ====Description==== * Official Symbol: FOXP2 * Chromosome: . . . including grammatical competence. Contents ====Phenotype==== There are several reasons for believing . . .
5K - last updated 2006-06-06 19:25 UTC by PeterDAdamo
FUT3
[[Nutrigenomics]] ====See Also==== * [[FUT1]] * [[FUT2]] * [[FUT4]] * [[19q13.3]] * [[Lewis antigens]] . . . donors with different ABO, secretor, and Lewis phenotypes. As previously reported, binding occurred . . . saliva from secretors, regardless of their Lewis phenotype status. Blood group B saliva was poorly recognized, . . .
6K - last updated 2006-05-06 12:06 UTC by PeterDAdamo
Factor VIII
[[Biochemistry]] ====See Also==== * [[Clotting factors]] * [[Rheology]] * [[Von Willebrand factor (vWF)]] . . . synergy between ABO and Secretor/Non-secretor phenotypes. In fact, secretor genetics appear to interact . . . researchers have suggested that the Le (a-b-) phenotype (and blood groups A, B, and AB especially), . . . KJ, Folsom AR, Liu K. Relationship among Lewis phenotype, clotting factors, and other cardiovascular . . . with blood groups A, B, or AB, and the Le(a-b-) phenotype, significantly higher levels of factor VIII . . .
10K - last updated 2006-06-27 10:25 UTC by PeterDAdamo
Gene-environment interaction
[[Genomics]] ====See Also==== * [[Conrad Hal Waddington]] * [[Epigenetics]] * [[Genotype]] * [[Genetic . . . * [[Jean-Baptiste de Lamarck (Lamarckism)]] * [[Phenotype]] * [[Pleiotropy]] ====Description==== Gene-environment . . .
3K - last updated 2006-06-02 22:44 UTC by PeterDAdamo
Genetic and environmental influences on somatotype components
[[Anthropometry]] ====See Also==== * [[Somatotype]] * [[Gene-environment interaction]] ====Abstracts==== . . . families from the Madrid, Spain, area. Each phenotype was adjusted for the effect of (1) age and . . . among correlations were assessed for each phenotype. No spouse resemblance was found for somatotype . . .
2K - last updated 2006-06-02 22:45 UTC by PeterDAdamo
H-h blood group system
[[Polymorphism]] ====See Also==== * [[Allele]] * [[Antigen]] * [[Blood group antigen proteins (chart)]] . . . 1992}}), who had "Bombay-like" red cell [[phenotype]]s and ABH nonsecretor phenotype in saliva. . . . to express active enzymes. The blood group [[phenotype]] of individuals bearing such alleles will . . . fully or partially inactivated.The H blood group phenotype is uniquely dependent on the expression of . . . either the Bombay or the para-Bombay blood group phenotype. In Bombay indivduals alleles of both FUT1 . . .
12K - last updated 2006-08-06 20:50 UTC by TomGreenfield
Hardy-Weinberg Principle
[[Genomics]] ====See Also==== * [[Allele]] * [[Genotype]] * [[Locus]] * [[Phenotype]] ====Description==== . . .
4K - last updated 2006-06-13 10:10 UTC by PeterDAdamo
Helicobacter pylori infection, ABO and secretor blood groups
[[Pathology]] ====See Also==== * [[ABH Antigens]] * [[Adhesins]] * [[Cell Adhesion Molecules (CAMs)]] . . . as compared with the individuals of the secretor phenotype. This might indicate that non-secretors are . . . or ABH non-secretors, with blood group O or A phenotypes was 37%. ({{Suadicani P, Hein HO, Gyntelberg . . . Individuals with Lewis (a+b-) ABH non-secretor phenotype also show a significantly higher proportion . . . with the individuals of Lewis (a-b+)/secretor phenotype. Evidence also indicates that 100% of non-secretors . . .
11K - last updated 2006-06-29 11:59 UTC by TomGreenfield
Histone
[[Genomics]] ====See Also==== * [[Allele]] * [[Chromatin]] * [[Chromosome]] * [[Deoxyribonucleic acid . . . methyltransferases (HMT)]] * [[Locus]] * [[Phenotype]] * [[RNA (ribonucleic acid)]] ====Description==== . . .
8K - last updated 2006-07-07 10:26 UTC by PeterDAdamo
Immunoglobulin E
[[Serology]] ====See also=== * [[Allergy]] * [[Allergy, ABO Blood Group and Secretor Status]] * [[Allergens, . . . to an additive effect of the two variables. M phenotype appears correlated positively with an increased . . . nonallergic asthma in all age groups, whereas N phenotype appears correlated positively with age at . . . GATA3, and STAT4 to asthma and high serum IgE phenotypes."> ====Attribution==== * This article . . .
6K - last updated 2006-05-12 09:24 UTC by PeterDAdamo
Inhibitory activity of blood group antigens M and N in inhibition of virus influenza hemagglutination
[[References]] ====Inhibitory activity of blood group antigens M and N in inhibition of virus influenza . . . Reactivity of erythrocytes with MM and NN phenotypes in titration of hemagglutinins of influenza . . . Reactivity of red blood cells with MM and NN phenotypes in retitration of haemagglutinins and inhibition . . . of O human red blood cells different in MN phenotype is identical in regard to speed of reaction . . . Human red cells with MM and NN phenotypes cause viral hemagglutination phenomenon . . .
3K - last updated 2006-06-10 17:54 UTC by TomGreenfield
Kell Blood Group
[[Polymorphism]] ====See Also==== * [[Allele]] * [[Antigen]] * [[Blood group systems]] * [[Glycoproteins]] . . . T, Redman C. ''Molecular basis of the Kell (K1) phenotype.'' Blood. 1995 Feb 15;85(4):912-6. PMID 7849312}}) . . . CY, Lin M. ''Molecular basis of the Kell-null phenotype: a mutation at the splice site of human KEL . . . The K<sub>0</sub> [[phenotype]] was first described in 1957 and the McLeod . . . phenotype was found in Hugh McLeod, a Harvard dental . . .
17K - last updated 2006-07-21 10:45 UTC by TomGreenfield
MC1R melanocortin 1 receptor (alpha melanocyte stimulating hormone receptor)
[[Nutrigenomics]] ====See Also==== ====Description==== * Species: Homo sapiens * Chromosome: 16; Location: . . . receptor has a role in skin cancer risk phenotypes through a polymorphism. [http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Retrieve&list_uids=12753400 . . .
2K - last updated 2006-05-25 10:01 UTC by PeterDAdamo
Maternal effect
[[Genomics]] ====See Also==== * [[Epigenetics]] * [[Genotype]] * [[Phenotype]] * [[Phenotypic plasticity]] . . . the genotype of a mother is expressed in the [[phenotype]] of its offspring, unaltered by paternal . . . because in maternal inheritance the individual's phenotype reflects its own [[genotype]], not necessarily . . .
2K - last updated 2006-06-24 19:05 UTC by PeterDAdamo
Mitochondrial genetics
[[Genomics]] ====See Also==== * [[Codon]] * [[Haplogroups]] * [[Mitochondria]] * [[Mitochrondrial DNA . . . normal Mendelian laws, despite the fact that the phenotype of the disease may be masked. Because of . . .
8K - last updated 2006-06-04 13:30 UTC by PeterDAdamo
Natural Selection in Man, The ABO(H) Blood Group System
[[Paleoserology]] ====See Also==== * [[William Boyd]] ====Natural Selection in Man: The ABO(H) Blood . . . distribution in the four different blood [[phenotype]]s in every population group. # The polymorphism . . . For example, it appears that individuals of phenotypes A and B are naturally eliminated at birth, . . . while natural mechanisms eliminate the O phenotypes at later ages. # The frequencies of the . . . were heterospecific with respect to the ABO(H) phenotypes. Since there are more childless matings . . .
3K - last updated 2006-05-21 05:14 UTC by AlanGoldenberg
O-linked glycosylation
[[Glycomics]] ====See Also==== * [[O-linked glycosylation]] * [[Glycosylation]] * [[Glycoproteins]] * . . . through O-linkage * Secreted in secretor phenotype * Attached sugar to ser/thr * Specific sugars . . .
1K - last updated 2006-04-21 12:06 UTC by ool-435621f6.dyn.optonline.net
Otitis (ear) infection and ABO blood groups
[[Pathology]] ====See Also==== * [[Oligosaccharide]] * [[Collectins]] ====Maternal blood group in otitis . . . development of cholesteatoma. ====Blood group phenotype determines lectin-mediated adhesion of Pseudomonas . . . Thus, the correlation between blood group A phenotype and P. aeruginosa-induced acute diffuse otitis . . .
4K - last updated 2006-04-28 10:44 UTC by PeterDAdamo
P (P1, P2) Blood Group
[[Polymorphism]] ====Description==== The biochemical nature of the antigens of the P blood group has . . . P1 blood group phenotype, secretor status in patients with urinary . . .
3K - last updated 2006-06-11 04:11 UTC by DonStJohn
Phenotype
[[Genomics]] ====Description==== The phenotype of an individual organism is either its total physical . . . or behavior that varies between individuals. Phenotype is determined to some extent by [[genotype]], . . . one or more positions on the chromosomes. Many phenotypes are determined by multiple genes and influenced . . . alleles does not always enable prediction of the phenotype. Nevertheless, because phenotypes are much . . . a person's eye color), classical genetics uses phenotypes to deduce the functions of genes. Breeding . . .
2K - last updated 2006-05-27 12:26 UTC by PeterDAdamo
Phenotypic plasticity
[[Genomics]] ====See Also==== * [[Genotype]] * [[Phenotype]] ====Description==== The ability of an organism . . . with a given [[genotype]] to change its [[phenotype]] in response to changes in the environment . . . of a range of environments to a range of phenotypes. Organisms of fixed genotype may differ . . . be adaptive if fitness is increased by changing phenotype. Immobile organisms such as plants have well . . . is due to a mismatch between a metabolic phenotype determined in development and the nutritional . . .
3K - last updated 2006-06-26 06:29 UTC by AlanGoldenberg
Pleiotropy
[[Genomics]] ====See Also==== * [[Genetic linkage]] * [[Phenotype]] ====Description==== The term pleiotropy . . .
3K - last updated 2006-06-19 07:09 UTC by AlanGoldenberg
Quantitative trait locus analysis
[[Genomics]] ====See Also==== * [[Epistasis]] * [[Genetic linkage]] * [[Haplotype]] * [[Phenotype]] ====Description==== . . . region of DNA is identified as contributing to a phenotype, it can be sequenced. The DNA sequence of . . . of the alleles which occur in a locus and the phenotypes (physical forms or traits) that they produce. . . . whether they produce a significant effect on the phenotype. QTLs identify a particular region of the . . . interested in understanding the genetic basis of phenotypes (what an organism looks like). The aim is . . .
6K - last updated 2006-06-27 10:51 UTC by PeterDAdamo
RNA (ribonucleic acid)
[[Genomics]] ====See Also==== * [[Allele]] * [[Chromosome]] * [[Deoxyribonucleic acid (DNA)]] * [[Genetic . . . * [[Nucleotide]] * [[Open reading frame]] * [[Phenotype]] ====Description==== A chain of nucleotides, . . .
6K - last updated 2006-07-06 11:10 UTC by PeterDAdamo
RNA Interference (RNAi)
[[Genomics]] ====See Also==== * [[Dicer]] * [[DNA]] * [[RNA]] * [[Translation (RNA translation)]] ====Description==== . . . spread from cell to cell and generate heritable phenotypes in first generation progeny when used in . . .
9K - last updated 2006-07-06 10:47 UTC by PeterDAdamo
Rheology
[[Polymorphism]] ====See Also==== * [[Clotting factors]] * [[Endothelial dysfunction]] * [[Factor VIII]] . . . Associations between the ABO phenotype and variations in blood rheology have been . . .
5K - last updated 2006-06-24 19:06 UTC by PeterDAdamo
Serum pepsinogen levels and ABO blood groups
[[Polymorphism]] ====See Also==== * [[Serum gastrin concentrations and ABO blood group]] * [[Pepsinogen]] . . . between serum pepsinogen levels, pepsinogen phenotypes, ABO blood groups, age and sex in blood . . . A (pepsinogen I) levels and urinary pepsinogen A phenotypes were studied in relation to ABO blood group, . . . was no relation between urinary pepsinogen A phenotypes and serum pepsinogen A levels. It is concluded . . . that serum PGA levels and PGA phenotypes are independent factors in predisposition . . .
3K - last updated 2006-04-26 12:36 UTC by PeterDAdamo
Soyasaponins
[[Pharmacology]] ====See Also==== * [[Saponins]] * [[Sialic acid and sialyltransferase dysfunction in . . . kinetics. Two distinct soyasaponin I degradation phenotypes were observed among the subjects: rapid . . . between the two soyasaponin degradation phenotypes. Two primary gut microbial metabolites of . . .
9K - last updated 2007-04-25 05:43 UTC by TomGreenfield
Spandrel
[[Concepts]] ====See Also==== * [[Phenotype]] * [[R.C. Lewontin]] ====Description==== Architecturally, . . .
2K - last updated 2006-06-28 12:49 UTC by PeterDAdamo
Thomsen-Friedenreich (T-Tn) antigen
[[Serology]] ====See Also==== * [[Mucin]] * [[Galectin 3, hGal-3]] * [[Neo-Springerism]] ====Description==== . . . gastric cancer related to ABO(H) blood-group phenotype. Int J Cancer 1995 Mar 16;60(6):781-785 Blood-group-A . . . gastric cancer related to ABO(H) blood-group phenotype.===== Int J Cancer 1995 Mar 16;60(6):781-785 . . . The relationship between the ABO(H)-blood-group phenotype and natural anti-TFA immune response in patients . . .
23K - last updated 2006-04-28 21:54 UTC by PeterDAdamo
49 pages found.
