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'A-Like' tumor antigens
[[Pathology]] ====See Also==== * [[Aberrent glycosylation in malignant and pre-malignant states]] * [[Forssman . . . as tumor markers, parasitic/bacterial/viral receptors, and their association with immunologically . . . epithelial cells. The P antigen is also the RBC receptor for Parvovirus B19. Leb has recently been . . . found to be the receptor for H. pylori in the gastric tissue. The high . . . frequency BGA, AnWj, is the RBC receptor for H. influenzae. BGAs have been shown to . . .
16K - last updated 2006-06-30 17:45 UTC by PeterDAdamo
7TM receptors
#REDIRECT [[G-protein-coupled receptors]] . . .
1K - last updated 2006-07-07 12:25 UTC by PeterDAdamo
ABO bias in natural immunity
[[Serology]] ====See Also==== * [[Agglutination]] * [[Flocculation]] * [[Isohemagglutinin Titer]] * [[Isohemagglutinins]] . . . bound monomeric IgM is the major antibody receptor used by B-lymphocytes to recognize antigen, . . .
18K - last updated 2006-05-11 15:54 UTC by PeterDAdamo
Aberrent glycosylation in malignant and pre-malignant states
[[Glycomics]] ====See Also==== * [['A-Like' tumor antigens]] * [[Thomsen-Friedenreich (T-Tn) antigen]] . . . [[apoptosis]], angiogenesis, growth factor receptors, [[integrins]] and [[cadherins]] function, . . .
7K - last updated 2006-06-04 05:43 UTC by AlanGoldenberg
Allergy
[[Immunology]] ====See Also==== * [[Basophils and Mast Cells]] * [[Immunoglobulin E]] * [[Leukotrienes]] . . . molecules travel through the blood and attach to receptors on the surface of mast cells. Different IgE . . . is some evidence that CD23 (the low-affinity IgE receptor) is in itself a C-type lectin.] [http://www.dadamo.com/wiki/wiki.pl/Dietary_lectins_can_induce_in_vitro_release_of_IL-4_and_IL-13_from_human_basophils . . . (hG3, epsilon BP [CBP 35] bind to IgE receptors. ====References==== 1. Cell Mol Life Sci . . .
6K - last updated 2006-05-31 07:27 UTC by AlanGoldenberg
Anti-adhesion therapy
[[Pharmacology]] ====See Also==== * [[Lectins]] * [[Fucus vesiculosis (Bladderwrack)]] ====Abstracts==== . . . to anti-adhesion therapy, including the use of receptor and adhesin analogs, dietary constituents, . . .
2K - last updated 2006-05-10 11:09 UTC by PeterDAdamo
ApoE
#REDIRECT [[Apolipoprotein E (APOE)]] ====Description==== Apolipoprotein E (APOE), a main apoprotein . . . of the chylomicron, binds to a specific receptor on liver cells and peripheral cells. APOE . . .
1K - last updated 2006-04-17 00:43 UTC by dhcp64-134-129-168.wbt.phx.wayport.net
Aquired B Phenotype
[[Immunology]] ====Description==== Acquired B state should be considered when the serum of a patient . . . anti-B sera do not react with the acquired B receptor. * If the patient is a [[secretor]], test . . .
2K - last updated 2006-04-19 20:35 UTC by ool-435621f6.dyn.optonline.net
Blood Groups and Anthropology
[[Paleoserology]] ====Attribution==== Excerpted from the Complete Blood Type Encyclopedia by Peter D'Adamo, . . . as tumor markers, parasitic/bacterial/viral receptors, and their association with immunologically . . .
48K - last updated 2006-05-26 06:48 UTC by AlanGoldenberg
Calcium binding atopy related auto-antigen 1 (CBARA1)
[[Nutrigenomics]] ====See Also==== * [[Atopy]] * [[Interleukin-5 (IL-5)]] * [[GATA-binding protein 3 . . . bind to IgE and induce cross-linking on IgE receptor-bearing [[Basophils and Mast Cells|mast cells . . .
2K - last updated 2006-05-12 12:36 UTC by PeterDAdamo
Changes in cell surface antigen expressions during proliferation and differentiation of human erythroid progenitors
[[References]] ====Changes in cell surface antigen expressions during proliferation and differentiation . . . GPIIb/IIIa, anti-HLA-DR, and antitransferrin receptor antibodies. Acid phosphatase staining was . . .
2K - last updated 2006-05-04 22:46 UTC by PeterDAdamo
Cholesterol and triglyceride levels, ABO blood groups and secretor status
[[Lipidomics]] ====See Also==== * [[Endothelial dysfunction]] * [[Cardiovascular disease, ABO blood groups . . . Among the genes transcribed are the LDL receptor and HMG-CoA reductase. The former scavenges . . .
19K - last updated 2006-07-04 11:42 UTC by PeterDAdamo
Complement System
[[Immunology]] ====See Also==== * [[Collectin]] * [[Opsonization]] * [[Mannan-binding lectin (MBL)]] . . . by a non-cytolytic mechanism through specific receptors present on various cell types. The direction . . . biological response depend on the state of the receptors (affinity and density) and on the function . . . of cells bearing receptors. From the functional standpoint, complement . . . receptors can be divided into two types: the adherent . . .
16K - last updated 2006-04-26 12:43 UTC by PeterDAdamo
Cyclic adenosine monophosphate (cAMP)
[[Biochemistry]] ====See Also==== * [[Alcoholism and Secretor Status]] * [[DRD2 (Dopamine Receptor D2) . . .
4K - last updated 2006-06-26 11:22 UTC by PeterDAdamo
DRD2 (Dopamine Receptor D2) Gene
[[Genomics]] ====See Also==== * [[Dopamine Beta-Hydroxylase (DBH)]] * [[Dopamine Beta Hydroxylase and . . . ABO Groups]] * [[DRD4 (Dopamine Receptor D4) Gene]] * [[Reduced platelet MAO activity . . . * Gene name: DRD2 * Gene description: dopamine receptor D2 * Chromosome: 11; Location: 11q23 * Organism: . . . This gene encodes the D2 subtype of the dopamine receptor. This G-protein coupled receptor inhibits . . . age-related decline was observed for dopamine receptor mRNAs in the hippocampus and entorhinal cortex. . . .
2K - last updated 2006-06-19 11:43 UTC by PeterDAdamo
Dimer
[[Biochemistry]] ====See Also==== In chemistry, a dimer refers to a molecule composed of two similar . . . usually upon the binding of a signal to the receptor of each monomer. These signals can be a growth . . . dimerizing activity involves the RAS-independent receptor tyrosine kinase that activates Phospholipase . . . to two monomeric Epithelial Growth Factor (EGF) receptor (or Platelet-Derived Growth Factor (PDGF) . . . receptor), the receptors will dimerize and phosphorylate . . .
3K - last updated 2006-05-05 10:51 UTC by PeterDAdamo
Duffy blood group system
[[Polymorphism]] ====See Also==== * [[Allele]] * [[Chemokines]] * [[Interleukin-8 (IL-8)]] FY Gene locus . . . gene codes for a protein known as a chemokine receptor, which is important in the inflammatory process. . . . Fy protein is also known as DARC (Duffy Antigen Receptor for Chenokines). The molecular basis for the . . . Duffy has been found to act as a multispecific receptor for [[chemokines]] of both the C-C and C-X-C . . . Fy protein is also known as DARC (Duffy Antigen Receptor for Chenokines). ====Tissue distribution==== . . .
15K - last updated 2006-05-14 19:52 UTC by PeterDAdamo
E. Coli Infection and ABO Blood Groups
[[Polymorphism]] ====See Also==== * [[Adhesins]] * [http://www.dadamo.com/lecster2/Lecster-read.pl?show=224 . . . G, Falk P, Jodal U, Leffler H, Svanborg C The receptor repertoire defines the host range for attaching . . .
11K - last updated 2006-05-04 22:03 UTC by PeterDAdamo
Effect of herbal melanin on IL-8. A possible role of Toll-like receptor 4 (TLR4)
[[References]] ====Effect of herbal melanin on IL-8: A possible role of Toll-like receptor 4 (TLR4)==== . . .
2K - last updated 2006-05-05 12:44 UTC by PeterDAdamo
Endocytosis
[[Physiology]] ====See Also==== * [[Lectins, Resistance to Degradation]] * [[Mucosa]] * [[Portal circulation]] . . . molecules such as proteins, membrane localized receptors and ion-channels. Uptake of extracellular . . . prompted after the binding of the protein to a receptor on the cell membrane. These receptors are . . . particles is also specifically mediated via receptors present in caveolae. ====Links==== . . .
3K - last updated 2006-05-15 14:25 UTC by PeterDAdamo
Endothelin
[[Physiology]] ====See Also==== * [[Kell Blood Group]] * [[Nitric Oxide]] * [[Prostacyclin]] ====Description==== . . . with varying regions of expression and two key receptor types, ETA and ETB. ETA is found in smooth . . . on endothelial cells and activation of this receptor increases natriuresis and diuresis and [[nitric . . . sometimes be treated by the use of an endothelin receptor antagonist such as bosentan or sitaxsentan. . . . production (although the effects of endothelin B receptors being activated depend on the type of host . . .
3K - last updated 2006-06-01 07:20 UTC by AlanGoldenberg
Epidermal Growth Factor (EGF)
[[Physiology]] ====See Also==== * [[Growth Factors]] ====Description==== Epidermal Growth Factor (EGF), . . . [[growth factors]], binds to very specialized receptors on the surface of responsive cells. Intrinsic . . . to the EGF receptor is tyrosine kinase activity, which is activated . . . gastric acid secretion. ====Discussion==== The receptor for EGF shares a similarity for the blood . . . in tests, antibodies directed against the EGF receptor also bind to the blood type A antigen as well. . . .
1K - last updated 2006-04-22 13:22 UTC by ool-435621f6.dyn.optonline.net
FUT3
[[Nutrigenomics]] ====See Also==== * [[FUT1]] * [[FUT2]] * [[FUT4]] * [[19q13.3]] * [[Lewis antigens]] . . . the Lewis(b) antigen, Le(b), is an epithelial receptor for H. pylori (see 600263). The H. pylori . . .
6K - last updated 2006-05-06 12:06 UTC by PeterDAdamo
G-protein-coupled receptors
[[Biochemistry]] ====See Also==== * [[Ligand]] * [[Receptor]] * [[Receptor antagonist]] * [[Second messengers]] . . . ====Description==== <b>G protein-coupled receptors (GPCRs)</b>, also known as seven transmembrane . . . receptors, heptahelical receptors, or <b>7TM . . . receptors</b>, are a protein family of transmembrane . . . receptors that transduce an extracellular signal (ligand . . .
10K - last updated 2006-07-08 10:41 UTC by PeterDAdamo
Genetic polymorphism of interleukin-8 (IL-8) is associated with Helicobacter pylori-induced duodenal ulcer
[[References]] ====Genetic polymorphism of interleukin-8 (IL-8) is associated with Helicobacter pylori-induced . . . polymorphism of the lipopolysaccharide (LPS) receptor CD14 and the formation of peptic ulcer, because . . .
3K - last updated 2006-05-05 12:29 UTC by PeterDAdamo
Glycoconjugates
[[Glycomics]] ====See Also==== * [[ABH Antigens]] * [[Carbohydrates as Biological Markers]] * [[Glycolipids]] . . . are for example tumor markers, enzymes, receptors, [[cytokines]] or antibodies. In naturally . . .
4K - last updated 2006-05-02 22:38 UTC by PeterDAdamo
Grave's Disease and secretor status
[[Pathology]] ====See Also==== * [[Non-secretors]] ====Secretor status and infection in patients with . . . express [[antigen]] cross reactive with the TSH receptor, we did not find an increased prevalence of . . .
2K - last updated 2006-05-29 06:21 UTC by AlanGoldenberg
H-h blood group system
[[Polymorphism]] ====See Also==== * [[Allele]] * [[Antigen]] * [[Blood group antigen proteins (chart)]] . . . FUT2 may serve as ligands in cell adhesion or as receptors for certain microorganisms. ====Tissue distribution==== . . .
12K - last updated 2006-08-06 20:50 UTC by TomGreenfield
Helicobacter pylori infection, ABO and secretor blood groups
[[Pathology]] ====See Also==== * [[ABH Antigens]] * [[Adhesins]] * [[Cell Adhesion Molecules (CAMs)]] . . . a strong involvement of selected [[Toll-like receptors (TLRs)|Toll-like receptors]], [[Cell Adhesion . . .
11K - last updated 2006-06-29 11:59 UTC by TomGreenfield
Histamine
[[Immunology]] ====See Also==== * [[Basophil]] ====Description==== http://biology.kenyon.edu/slonc/bio3/amino_acids/Histidine/histamine%20structure.gif . . . antigen must first be attached to cell surface receptors on mast cells. Antigen binding to the mast . . . Pharmacology. XIII. Classification of Histamine Receptors] . . .
2K - last updated 2006-06-02 07:08 UTC by AlanGoldenberg
Homeostasis
[[Physiology]] ====See Also==== '''Homeostasis''' is the property of an open system, especially living . . . When body temperature rises (or falls), receptors in the skin and the hypothalamus sense a . . .
7K - last updated 2006-05-27 15:03 UTC by TomGreenfield
Hypothalamic-pituitary-adrenal axis (HPA axis)
[[Physiology]] ====See Also==== * [[Cortisol]] ====Description==== The '''hypothalamic-pituitary-adrenal . . . In the brain, cortisol acts at two types of receptor - mineralocorticoid receptors and glucocorticoid . . . receptors, and these are expressed by many different . . .
9K - last updated 2006-08-20 07:05 UTC by TomGreenfield
Immunoglobulin E
[[Serology]] ====See also=== * [[Allergy]] * [[Allergy, ABO Blood Group and Secretor Status]] * [[Allergens, . . . long-lived interaction with its high affinity receptor, Fc epsilon RI, so that basophils and mast . . . cells is thought to involve the "low affinity" receptor, Fc epsilon RII or CD23. CD23 may also allow . . .
6K - last updated 2006-05-12 09:24 UTC by PeterDAdamo
Inhibitory activity of blood group antigens M and N in inhibition of virus influenza hemagglutination
[[References]] ====Inhibitory activity of blood group antigens M and N in inhibition of virus influenza . . . is identical in regard to speed of reaction and receptor capacity in titration, retitration and inhibition . . . means that M and N blood group antigens contain receptors for influenza virus. '''CONCLUSIONS''': Human . . . identically in view of speed of reaction and receptor capacity, and have the same impact on result . . . phenomenon, because they do not contain receptors for viral hemagglutinin on red cell membrane . . .
3K - last updated 2006-06-10 17:54 UTC by TomGreenfield
Interleukin-1 (IL-1)
[[Immunology]] ====See Also==== * [[Toll-like receptors (TLRs)]] * [[Interleukin-6 (IL-6)]] * [[Cytokines]] . . . two forms of IL-1 bind to the same cellular receptor. This receptor is composed of two related, . . . pathway that is mostly shared with certain other receptors. These include the Toll family of innate . . . immune receptors and the receptor for IL-18. The IL-1 receptor . . . IL-1Ra, is an agent which binds to the same receptor on the cell surface as IL-1, and thus prevents . . .
4K - last updated 2006-05-13 10:00 UTC by PeterDAdamo
Interleukin-4 (IL-4)
[[Immunology]] ====See Also==== * [[Dietary lectins can induce in vitro release of IL-4 and IL-13 from . . . of these cells following binding to cell surface receptors. The amino acid sequence of its extracellular . . . defined it as a member of the hematopoietin receptor superfamily. [[Polymorphism|Polymorphisms]] . . . in the alpha subunit of the interleukin-4 receptor. New Eng. J. Med. 337: 1720-1725, 1997}}) . . . in the cytoplasmic domain of the interleukin-4 receptor alpha protein. The R576 allele was found in . . .
4K - last updated 2006-05-17 00:54 UTC by AlanGoldenberg
Interleukin-5 (IL-5)
[[Immunology]] ====See Also==== * [[Atopy]] * [[Cytokines]] * [[GATA-binding protein 3 (GATA3)]] * [[T . . . lymphocytes. =====Retinoic acid modulates IL-5 receptor expression and selectively inhibits eosinophil-basophil . . . exerting its effects through the IL-5 receptor (IL-5Ralpha). Currently, little is known concerning . . . inhibition of IL-5Ralpha but no change in GM-CSF receptor expression, as detected with flow cytometry. . . . expression of IL-5Ralpha, but not GM-CSF receptor, and that these effects have functional consequences . . .
5K - last updated 2006-05-12 12:27 UTC by PeterDAdamo
Interleukin-6 (IL-6)
[[Immunology]] ====See Also==== * [[Cytokines]] * [[Tumor Necrosis Factor (TNF)]] * [[Toll-like receptors . . . molecular patterns (PAMPs) binding the Toll-like Receptor (TLR) present on an active macrophage. IL-6 . . . Br J Surg. 1998 Dec;85(12):1658-62.}}) The IL-6 receptor is found on many cell surfaces, including . . . IL-6 mediates its responses through cell surface receptors that include the transmambrane protein gp130. . . . of protein complexes of gp130 and the IL-6 receptor activating the receptor. These complexes bring . . .
5K - last updated 2006-05-31 18:11 UTC by PeterDAdamo
Interleukin-7 (IL-7)
[[Immunology]] ====See Also==== * [[Cytokines]] * [[Longevity]] * [[MUC1 Mucin]] ====Description==== . . . in the alpha chain of the IL-7 receptor in patients with severe combined immunodeficiency . . .
4K - last updated 2006-05-17 01:05 UTC by AlanGoldenberg
Kell Blood Group
[[Polymorphism]] ====See Also==== * [[Allele]] * [[Antigen]] * [[Blood group systems]] * [[Glycoproteins]] . . . 1976;26(4):267-71. PMID 976995}}) Bitter taste receptor proteins in the taste buds of the tongue that . . .
17K - last updated 2006-07-21 10:45 UTC by TomGreenfield
Kupffer cell
[[Immunology]] ====See Also==== * [[Alternate Complement Pathway]] * [[Cytokines]] * [[Endotoxin]] * . . . into Kupffer cells. Helmy et al. identified a receptor present in Kupffer cells, the complement receptor . . .
7K - last updated 2006-06-10 00:27 UTC by AlanGoldenberg
Leptin (LEP, obesity homolog)
[[Nutrigenomics]] ====See Also==== * [[INSIG2 (Insulin Induced Gene 2)]] * [[Tumor Necrosis Factor alpha . . . the ob [[gene]] or the gene encoding the leptin receptor (db gene) have been known for many years and . . . of satiety, and differences in the gene for the receptor at which α-MSH acts in the brain are linked . . .
6K - last updated 2006-06-22 11:45 UTC by PeterDAdamo
Ligand
[[Biochemistry]] ====See Also==== * [[Agonist]] * [[G-protein-coupled receptors]] * [[Receptor]] * [[Receptor . . . with positron emission tomography to study the receptor systems of the brain. In basic biology, ligands . . . attach to receptors as a way of cytoplasmic signaling in a cell. . . . The two main types of receptors that these ligands can attach to are soluble . . . cytoplasmic proteins or transmembrane receptors. An example of a cytoplasmic protein is a . . .
5K - last updated 2006-07-08 10:37 UTC by PeterDAdamo
MC1R melanocortin 1 receptor (alpha melanocyte stimulating hormone receptor)
[[Nutrigenomics]] ====See Also==== ====Description==== * Species: Homo sapiens * Chromosome: 16; Location: . . . * Official Symbol: MC1R and Name: melanocortin 1 receptor (alpha melanocyte stimulating hormone receptor) . . . This intronless gene encodes the receptor protein for melanocyte-stimulating hormone . . . a seven pass transmembrane G protein coupled receptor, controls melanogenesis. Two types of melanin . . . upon UV radiation. Binding of MSH to its receptor activates the receptor and stimulates eumelanin . . .
2K - last updated 2006-05-25 10:01 UTC by PeterDAdamo
MUC1 Mucin
[[Glycomics]] ====See Also==== * [[Mucin]] * [[Aberrent glycosylation in malignant and pre-malignant . . . has been shown to associate with all four erbB receptors and localize with erbB1 (EGFR) in lactating . . .
4K - last updated 2006-05-03 22:50 UTC by PeterDAdamo
Microvilli
[[Physiology]] ====See Also==== * [[Villi]] * [[Mucosa]] * [[Lectins]] * [[Polyamines]] ====Description==== . . . in the cells of taste buds, and in olfactory receptor cells. They are observed on the plasma surface . . .
5K - last updated 2006-04-22 12:43 UTC by ool-435621f6.dyn.optonline.net
Mitogen
[[Immunology]] ====See Also==== * [[Lectins, Mitogen and Blastogenic Effects]] * [[Blastogenesis]] * . . . work, it appears that cross-linking of surface receptors is a crucial event in B-cell activation. . . .
2K - last updated 2006-04-25 20:01 UTC by PeterDAdamo
Myeloperoxidase
[[Immunology]] ====Description==== Myeloperoxidase is a lysosomal enzyme that is found in white blood . . . binding of formylated peptides to chemotactic receptors, and influences other functions in stimulated . . .
6K - last updated 2006-04-19 20:57 UTC by ool-435621f6.dyn.optonline.net
Natural Killer (NK) Cells
[[Immunology]] ====See Also==== * [[T lymphocyte]] * [[Cell mediated immunity]] * [[Cytokines]] ====Definition==== . . . have several very specialized [[lectin]]-like receptors that recognize [[Major Histocompatibility . . . J Clin Immunol 1996 Sep;16(5):243-53}}) These receptors express several type II [[glycoproteins]] . . .
8K - last updated 2006-05-03 21:02 UTC by PeterDAdamo
Opsonization
[[Immunology]] ====See Also==== * [[Mannan-binding lectin (MBL)]] * [[Collectin]] * [[Macrophage]] * . . . complement molecules. Phagocytic cells express receptors that bind opsonin molecules. With the antigen . . . C3b molecule of the complement system. Each has receptors for both foreign particle and host phagocyte. . . . will cause increased expression of complement receptors on neighboring phagocytes. Examples of opsonin . . .
3K - last updated 2006-04-25 20:55 UTC by PeterDAdamo
Peptidoglycan
[[Immunology]] ====See Also==== * [[Pattern recognition receptors]] ====Description==== Peptidoglycan, . . .
3K - last updated 2006-05-21 06:48 UTC by AlanGoldenberg
Platelets
[[Immunology]] ====See Also==== * [[Rheology]] * [[Factor VIII]] * [[Clotting factors]] ====Description==== . . . thrombin (primarily through PAR-1), ADP, with receptors expressed on white blood cells or the endothelial . . .
2K - last updated 2006-04-20 22:39 UTC by ool-435621f6.dyn.optonline.net
Receptor
[[Biochemistry]] ====See Also==== * [[G-protein-coupled receptors]] * [[Ligand]] * [[Receptor antagonist]] . . . ====Description==== In biochemistry, a <b>receptor</b> is a protein on the cell membrane . . . Ligand-induced changes in the behavior of receptor proteins result in physiological changes that . . . Transmembrane receptor:E=extracellular space; I=intracellular space; . . . P=plasma membrane ====Receptor Types==== Receptors exist in different types, . . .
5K - last updated 2006-07-08 10:37 UTC by PeterDAdamo
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor)
[[Genomics]] ====See Also==== * [[G Quartet oligonucleotides]] * [[Interleukin-6 (IL-6)]] * [[Transcription . . . STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or . . .
3K - last updated 2006-05-31 18:22 UTC by PeterDAdamo
Sialic acid and sialyltransferase dysfunction in breast cancer
[[Pathology]] ====See Also==== * [[Glycomics]] * [[Soyasaponins]] * [[Sialotransferases]] ====Discussion==== . . . histoprognostic grading and steroid hormone receptor status. RESULTS: The median follow-up was . . . 7.5 years. Expression of estrogen receptors was associated with a good prognosis for . . .
2K - last updated 2006-05-01 21:35 UTC by PeterDAdamo
Sialogens
[[Glycomics]] ====See Also==== * [[E. Coli Infection and ABO Blood Groups]] * [[Mucin]] * [[Alternate . . . complementarity of the glycoprotein to the viral receptor. Several glycoproteins, including [[N-acetylgalactosamine]] . . . sialoglycoproteins on the RBC's seem to be receptors for Plasmodium falciparum merozoites. ====Links==== . . .
5K - last updated 2006-04-25 09:16 UTC by TomGreenfield
Siglecs
[[Lectinology]] ====See Also==== * [[19q13.3]] * [[Carbohydrates as Biological Markers]] * [[Cell Adhesion . . . Siglecs are a group of adhesion receptors with tyrosine-based inhibitory signaling . . . macrophages, or as an Sn-Rg [sialoadhesion-receptor globulin] construct) shows marked preference . . .
9K - last updated 2006-05-06 10:14 UTC by PeterDAdamo
Signal transduction
[[Physiology]] ====See Also==== * [[Nitric Oxide]] * [[Proteasome]] * [[Second messengers]] ====Description==== . . . cells to communicate across synapses, bind to receptor proteins in the membrane and open their ion . . . binding of extracellular signaling molecules to receptors that face outwards from the membrane and . . . via a change in the shape or conformation of the receptor which occurs when the signal molecule "docks" . . . or binds. Receptors typically respond only to the specific molecule . . .
21K - last updated 2006-07-07 11:58 UTC by PeterDAdamo
Thromboxanes
[[Lipidomics]] ====See Also==== * [[Leukotrienes]] * [[Eicosanoid]] * [[Prostaglandins]] ====Description==== . . . of platelets. Circulating fibrinogen binds these receptors on adjacent platelets, further strengthening . . .
2K - last updated 2006-07-04 11:42 UTC by PeterDAdamo
Toll-like receptors (TLRs)
[[Immunology]] ====See Also==== * [[Interleukin-1 (IL-1)]] * [[Interleukin-6 (IL-6)]] * [[Interleukin-8 . . . [[Growth Factors]] ====Description==== Toll-like receptors (TLRs) type I transmembrane proteins that . . . immune responses. TLR are pattern recognition receptors (PRRs), binding to pathogen-associated molecular . . . fly's immunity to fungal infections. Toll-like receptors in mammals were identified in 1997. http://www.dadamo.com/wiki/tlr.jpg . . . Original image] ====Receptors==== It has been estimated that most mammalian . . .
8K - last updated 2006-05-23 07:33 UTC by AlanGoldenberg
Toxin
[[Biochemistry]] ====See Also==== * [[Hapten]] * [[Endotoxin]] ====Description==== A toxin (Gk. toxikon . . . macromolecules such as enzymes or cellular receptors. Toxins vary greatly in their severity, ranging . . . each targeting a specific nerve channel or receptor), or relatively small protein. ====Use==== . . .
3K - last updated 2006-06-05 07:38 UTC by TomGreenfield
Trp64Arg polymorphism, body composition, insulin resistance and bioimpedance (BIA)
[[References]] ====Energy expenditure, body composition and insulin response to glucose in male twins . . . Trp64Arg polymorphism of the beta3-adrenergic receptor gene==== Diabetes Obes Metab. 2006 May;8(3):322-30. . . . (Trp64Arg) polymorphism of the beta3-adrenergic receptor (beta3AR) gene has been associated with an . . .
3K - last updated 2006-05-08 13:06 UTC by PeterDAdamo
Trp64Arg polymorphism of the beta3-adrenergic receptor gene
[[Polymorphism]] ====See Also==== * [[Mutation]] ====Description==== There is a possible association . . . and insulin resistance (IR). The ß3-adrenergic receptor (ß3-AR) is mainly expressed in adipose tissue . . . and genetic variation in the ß3-adrenergic-receptor gene. N Engl J Med1995; 333: 343–347}}). . . . of a polymorphism in the ß3-adrenergic-receptor gene with features of the insulin resistance . . . K et al. A mutation in the ß3-adrenergic receptor gene is associated with obesity and hyperinsulinemia . . .
3K - last updated 2006-05-24 06:59 UTC by AlanGoldenberg
Ubiquitin
[[Genomics]] ====See Also==== * [[Proteasome]] * [[RNA]] * [[Translation (RNA translation)]] ====Description==== . . . also mark transmembrane proteins (for example, receptors) for removal from membranes and fulfill several . . .
7K - last updated 2006-07-07 11:47 UTC by PeterDAdamo
Uncoupling protein 1 (UCP1, mitochondrial, proton carrier)
[[Nutrigenomics]] ====See Also==== * [[INSIG2 (Insulin Induced Gene 2)]] * [[Mitochondria]] * [[Trp64Arg . . . polymorphism of the beta3-adrenergic receptor gene]] ====UCP1 uncoupling protein 1 (mitochondrial, . . . the Trp64Arg mutation of the beta 3-adrenergic receptor gene on weight gain in morbid obesity.===== . . .
5K - last updated 2006-06-22 11:45 UTC by PeterDAdamo
Von Willebrand factor (vWF)
[[Biochemistry]] ====See Also==== * [[Factor VIII]] * [[Clotting factors]] ====Description==== <b>Von . . . the A1 domain, which binds to: ** platelet gp1b-receptor ** heparin ** possibly collagen * the A3 domain, . . . see below). * vWF binds to other platelet receptors when they are activated, e.g., by thrombin . . .
6K - last updated 2007-05-29 03:53 UTC by AlanGoldenberg
What's New
<table><tr><td> http://www.dadamo.com/wiki/coral-sm.jpg </td><td>Articles . . . 1" "Adenine" "Nucleotide" "Transcriptome" "Receptor antagonist" "G-protein-coupled receptors" . . . "Ligand" "Receptor" "Signal transduction" "Proteasome" "Ubiquitin" . . .
2K - last updated 2007-08-20 01:47 UTC by AlanGoldenberg
67 pages found.