{"id":607,"date":"2020-02-19T09:45:45","date_gmt":"2020-02-19T09:45:45","guid":{"rendered":"https:\/\/dadamo.com\/dangerous\/?p=607"},"modified":"2020-03-19T10:12:43","modified_gmt":"2020-03-19T10:12:43","slug":"building-an-anti-coronaviral-database","status":"publish","type":"post","link":"https:\/\/dadamo.com\/dangerous\/2020\/02\/19\/building-an-anti-coronaviral-database\/","title":{"rendered":"Covid-19: Building an anti-coronaviral database"},"content":{"rendered":"

I’ve been building a database of potential agents (drugs, botanical, supplements and foods) that have some evidence basis behind their use as antivirals against the novel coronavirus.<\/p>\n

\"\"<\/p>\n

The online database can be accessed here.<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"

I’ve been building a database of potential agents (drugs, botanical, supplements and foods) that have some evidence basis behind their use as antivirals against the novel coronavirus. The online database can be accessed here.<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"spay_email":"","jetpack_publicize_message":"","jetpack_is_tweetstorm":false},"categories":[16,23],"tags":[],"jetpack_featured_media_url":"","jetpack_publicize_connections":[],"jetpack_sharing_enabled":true,"jetpack_shortlink":"https:\/\/wp.me\/paaqQX-9N","jetpack-related-posts":[{"id":511,"url":"https:\/\/dadamo.com\/dangerous\/2018\/09\/24\/building-an-ai-inspired-herbal-pinpointer\/","url_meta":{"origin":607,"position":0},"title":"Building an AI-based botanical medicine indicator","date":"September 24, 2018","format":false,"excerpt":"I've been exploring artificial intelligence (AI) modules from the Comprehensive Perl Archive Network (CPAN), a great resource for legally stealing very useful tools made by people far smarter than me. One of their featured machine learning modules is also one of the simplest. It's called the 'Naive Bayes' algorithm. I\u2026","rel":"","context":"In "Artificial Intelligence"","img":{"alt_text":"","src":"https:\/\/i2.wp.com\/dadamo.com\/dangerous\/wp-content\/uploads\/2018\/09\/energetics.png?resize=350%2C200&ssl=1","width":350,"height":200},"classes":[]},{"id":489,"url":"https:\/\/dadamo.com\/dangerous\/2018\/09\/01\/pathfinding-gene-circuits\/","url_meta":{"origin":607,"position":1},"title":"Pathfinding gene circuits","date":"September 1, 2018","format":false,"excerpt":"The UB\/COEGM Pathfinder Scholarship Program is a partnership between the University of Bridgeport School of Health Sciences and the Center of Excellence in Generative Medicine. Its mission is to groom developing physicians in the skills of twenty-first century precision medicine through the use of bioinformatics. It's been my honor and\u2026","rel":"","context":"In "Bioinformatics"","img":{"alt_text":"","src":"https:\/\/i2.wp.com\/dadamo.com\/dangerous\/wp-content\/uploads\/2018\/09\/group.jpg?fit=1000%2C681&ssl=1&resize=350%2C200","width":350,"height":200},"classes":[]},{"id":1005,"url":"https:\/\/dadamo.com\/dangerous\/2021\/04\/29\/clinical-decisions-support-systems-i-known-unknowns\/","url_meta":{"origin":607,"position":2},"title":"Clinical Decisions Support Systems I: Known Unknowns","date":"April 29, 2021","format":false,"excerpt":"1. \u00a0Rheingold: Interactive Interactions Who among us has not had a client or a friend that was currently on a bouillabaisse of 3-4 pharmaceuticals and perhaps 5-6 (or more) dietary supplements?\u00a0 Ever wonder what exactly was going in there? Perhaps a nifty little app I recently coded might be just\u2026","rel":"","context":"In "Bioinformatics"","img":{"alt_text":"","src":"https:\/\/i0.wp.com\/dadamo.com\/dangerous\/wp-content\/uploads\/2021\/04\/rhythmus3.png?fit=1188%2C806&ssl=1&resize=350%2C200","width":350,"height":200},"classes":[]},{"id":823,"url":"https:\/\/dadamo.com\/dangerous\/2020\/04\/06\/covid-19-fiery-falling\/","url_meta":{"origin":607,"position":3},"title":"Covid-19: Pyroptosis, a Fiery Falling","date":"April 6, 2020","format":false,"excerpt":"A rush is on to understand what underpins the progression of Covid-19 from a mild flu-like presentation, to out-of-control pneumonia, and ultimately, system-wide collapse. We know some factors (comorbidities) that tend to increase the risk of severe consequences of Covid-19, such as age, gender, high blood pressure, and even ABO\u2026","rel":"","context":"In "Bioinformatics"","img":{"alt_text":"","src":"https:\/\/i0.wp.com\/dadamo.com\/dangerous\/wp-content\/uploads\/2020\/04\/Odins_last_words_to_Baldr.jpg?fit=1200%2C886&ssl=1&resize=350%2C200","width":350,"height":200},"classes":[]},{"id":747,"url":"https:\/\/dadamo.com\/dangerous\/2020\/04\/04\/covid-19-ace2\/","url_meta":{"origin":607,"position":4},"title":"Covid-19: The ACE2 of Spades","date":"April 4, 2020","format":false,"excerpt":"Angiotensin-converting enzyme 2 (ACE2), a protein on the surface of the cell membrane, is now at center-stage in this outbreak as the key receptor for the spike glycoprotein of SARS-CoV-2. ACE2 is part of renin\u2013angiotensin\u2013aldosterone system (RAAS) is an elegant cascade of protein linkages that orchestrate key processes in human\u2026","rel":"","context":"In "Bioinformatics"","img":{"alt_text":"","src":"https:\/\/i0.wp.com\/dadamo.com\/dangerous\/wp-content\/uploads\/2020\/04\/barabasi.jpg?fit=640%2C414&ssl=1&resize=350%2C200","width":350,"height":200},"classes":[]},{"id":624,"url":"https:\/\/dadamo.com\/dangerous\/2020\/03\/10\/covid-19-no-pussyfooting\/","url_meta":{"origin":607,"position":5},"title":"Covid-19: No Pussyfooting.","date":"March 10, 2020","format":false,"excerpt":"Covid19: 03\/10\/2020 Not for nothing, but by my calculations the chaos in the US and other secondary countries will hit in about 9-14 days. Use the next few days to get prepared for your own distancing, and make sure the sick and old geezers you look after are in at\u2026","rel":"","context":"In "Covid19"","img":{"alt_text":"","src":"","width":0,"height":0},"classes":[]}],"_links":{"self":[{"href":"https:\/\/dadamo.com\/dangerous\/wp-json\/wp\/v2\/posts\/607"}],"collection":[{"href":"https:\/\/dadamo.com\/dangerous\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/dadamo.com\/dangerous\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/dadamo.com\/dangerous\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/dadamo.com\/dangerous\/wp-json\/wp\/v2\/comments?post=607"}],"version-history":[{"count":2,"href":"https:\/\/dadamo.com\/dangerous\/wp-json\/wp\/v2\/posts\/607\/revisions"}],"predecessor-version":[{"id":615,"href":"https:\/\/dadamo.com\/dangerous\/wp-json\/wp\/v2\/posts\/607\/revisions\/615"}],"wp:attachment":[{"href":"https:\/\/dadamo.com\/dangerous\/wp-json\/wp\/v2\/media?parent=607"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/dadamo.com\/dangerous\/wp-json\/wp\/v2\/categories?post=607"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/dadamo.com\/dangerous\/wp-json\/wp\/v2\/tags?post=607"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}