{"id":643,"date":"2020-01-26T21:05:37","date_gmt":"2020-01-26T21:05:37","guid":{"rendered":"https:\/\/dadamo.com\/dangerous\/?p=643"},"modified":"2020-03-19T21:12:37","modified_gmt":"2020-03-19T21:12:37","slug":"wuhan-coronavirus-mannose-binding-lectins-are-inhibitors-of-sars-like-coronaviruses","status":"publish","type":"post","link":"https:\/\/dadamo.com\/dangerous\/2020\/01\/26\/wuhan-coronavirus-mannose-binding-lectins-are-inhibitors-of-sars-like-coronaviruses\/","title":{"rendered":"Wuhan Coronavirus : Mannose-binding lectins are inhibitors of SARS-like coronaviruses"},"content":{"rendered":"<p>Mannose-binding lectins are inhibitors of SARS-like coronaviruses. Best food sources of mannose-binding lectins? Monocots, such as leeks, garlic and onions. Fresh crushed garlic probably best. <\/p>\n<p>Mannose binding lectin (MBL)  is also made internally via the MBL2 gene as part of the body&#8217;s immune complement system. Low levels of  MBL are well-associated with immune compromise, most famously repeat ear infections in kids, and variations of the MBL2 gene are though to be responsible for the fact that between 7% and 30% of the population among Western countries is deficient in serum mannose-binding lectins. <\/p>\n<p>Perhaps another strategy might be to work on increasing one&#8217;s own internal MBL. <\/p>\n<p>Here are a few possible options<\/p>\n<ul>\n<li>Vitamin D (supplement or sunlight). MBL levels are known to drop during wintertime.<\/li>\n<li>Avoiding second hand smoke<\/li>\n<li>Larch arabinogalactan (increases MBL2 in two studies; one with humans)<\/li>\n<\/ul>\n<p><a href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0166354207002380?\">Plant lectins are potent inhibitors of coronaviruses by interfering with two targets in the viral replication cycle<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Mannose-binding lectins are inhibitors of SARS-like coronaviruses. Best food sources of mannose-binding lectins? Monocots, such as leeks, garlic and onions. Fresh crushed garlic probably best. Mannose binding lectin (MBL) is also made internally via the MBL2 gene as part of the body&#8217;s immune complement system. Low levels of MBL are well-associated with immune compromise, most<\/p>\n<p><a href=\"https:\/\/dadamo.com\/dangerous\/2020\/01\/26\/wuhan-coronavirus-mannose-binding-lectins-are-inhibitors-of-sars-like-coronaviruses\/\" class=\"more-link themebutton\">Read More<\/a><\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"spay_email":"","jetpack_publicize_message":"","jetpack_is_tweetstorm":false},"categories":[23],"tags":[],"jetpack_featured_media_url":"","jetpack_publicize_connections":[],"jetpack_sharing_enabled":true,"jetpack_shortlink":"https:\/\/wp.me\/paaqQX-an","jetpack-related-posts":[{"id":685,"url":"https:\/\/dadamo.com\/dangerous\/2020\/03\/24\/covid-19-stinging-nettle-lectin\/","url_meta":{"origin":643,"position":0},"title":"Covid-19: Stinging Nettle Lectin","date":"March 24, 2020","format":false,"excerpt":"\"Out of this nettle - danger - we pluck this flower - safety.\u201d --- William Shakespeare When I think of nettles, I remember an observation one of my student classmates at John Bastyr College shared with me that he had learned in an undergraduate botany class. Stinging nettles (Urtica spp.)\u2026","rel":"","context":"In &quot;Covid19&quot;","img":{"alt_text":"","src":"https:\/\/i2.wp.com\/dadamo.com\/dangerous\/wp-content\/uploads\/2020\/03\/stinging-nettle-2467988_1280.jpg?fit=800%2C1200&ssl=1&resize=350%2C200","width":350,"height":200},"classes":[]},{"id":620,"url":"https:\/\/dadamo.com\/dangerous\/2020\/03\/20\/covid-19-blood-type\/","url_meta":{"origin":643,"position":1},"title":"Covid-19:  ABO Blood Type","date":"March 20, 2020","format":false,"excerpt":"\u00a0 The media was awash with reports of a preprint (not-peer reviewed) report that individuals who are blood type A might be at more risk of Covid19 infection than those who are type O. The study was conducted by scientists and doctors from cities across China including Beijing, Wuhan, Shanghai\u2026","rel":"","context":"In &quot;Covid19&quot;","img":{"alt_text":"","src":"https:\/\/i1.wp.com\/dadamo.com\/dangerous\/wp-content\/uploads\/2020\/03\/rbc.jpg?fit=958%2C651&ssl=1&resize=350%2C200","width":350,"height":200},"classes":[]},{"id":354,"url":"https:\/\/dadamo.com\/dangerous\/2018\/08\/27\/mushroom-cloud\/","url_meta":{"origin":643,"position":2},"title":"Mushroom cloud","date":"August 27, 2018","format":false,"excerpt":"Studies are increasingly indicating that almost any change you make to the diet changes your gut microbiota. Those changes might be slight, and in fact difficult to predict from person to person, but they are there. Now new research seems to indicate that eating white button mushrooms daily can act\u2026","rel":"","context":"In &quot;Lectins&quot;","img":{"alt_text":"","src":"https:\/\/i2.wp.com\/dadamo.com\/dangerous\/wp-content\/uploads\/2018\/08\/ChampignonMushroom.jpg?fit=800%2C570&ssl=1&resize=350%2C200","width":350,"height":200},"classes":[]},{"id":747,"url":"https:\/\/dadamo.com\/dangerous\/2020\/04\/04\/covid-19-ace2\/","url_meta":{"origin":643,"position":3},"title":"Covid-19: The ACE2 of Spades","date":"April 4, 2020","format":false,"excerpt":"Angiotensin-converting enzyme 2 (ACE2), a protein on the surface of the cell membrane, is now at center-stage in this outbreak as the key receptor for the spike glycoprotein of SARS-CoV-2. ACE2 is part of renin\u2013angiotensin\u2013aldosterone system (RAAS) is an elegant cascade of protein linkages that orchestrate key processes in human\u2026","rel":"","context":"In &quot;Bioinformatics&quot;","img":{"alt_text":"","src":"https:\/\/i0.wp.com\/dadamo.com\/dangerous\/wp-content\/uploads\/2020\/04\/barabasi.jpg?fit=640%2C414&ssl=1&resize=350%2C200","width":350,"height":200},"classes":[]},{"id":719,"url":"https:\/\/dadamo.com\/dangerous\/2020\/04\/01\/covid-19-melatonin\/","url_meta":{"origin":643,"position":4},"title":"Covid-19: Melatonin","date":"April 1, 2020","format":false,"excerpt":"Most of us have heard of, or even occasionally used the supplement melatonin. It is the most popular over-the-counter sleep remedy in the US, resulting in sales in excess of US $400 million during 2017. Melatonin is a hormone that is primarily released by the pineal gland in the brain\u2026","rel":"","context":"In &quot;Covid19&quot;","img":{"alt_text":"","src":"https:\/\/i0.wp.com\/dadamo.com\/dangerous\/wp-content\/uploads\/2020\/04\/sleep.jpg?fit=800%2C547&ssl=1&resize=350%2C200","width":350,"height":200},"classes":[]},{"id":605,"url":"https:\/\/dadamo.com\/dangerous\/2020\/03\/14\/covid19-why-older-people-get-hit-harder\/","url_meta":{"origin":643,"position":5},"title":"Covid-19:  Why older people get hit harder","date":"March 14, 2020","format":false,"excerpt":"I've heard again and again about how the reason that older people are more impacted by Covid19 is due to their diminished immune system capacity. This seemed from the start to make little sense to me. I mean, if their immune systems were degraded, they'd have less acute inflammation as\u2026","rel":"","context":"In &quot;Covid19&quot;","img":{"alt_text":"","src":"https:\/\/i0.wp.com\/dadamo.com\/dangerous\/wp-content\/uploads\/2020\/03\/old.jpg?fit=1200%2C800&ssl=1&resize=350%2C200","width":350,"height":200},"classes":[]}],"_links":{"self":[{"href":"https:\/\/dadamo.com\/dangerous\/wp-json\/wp\/v2\/posts\/643"}],"collection":[{"href":"https:\/\/dadamo.com\/dangerous\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/dadamo.com\/dangerous\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/dadamo.com\/dangerous\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/dadamo.com\/dangerous\/wp-json\/wp\/v2\/comments?post=643"}],"version-history":[{"count":1,"href":"https:\/\/dadamo.com\/dangerous\/wp-json\/wp\/v2\/posts\/643\/revisions"}],"predecessor-version":[{"id":646,"href":"https:\/\/dadamo.com\/dangerous\/wp-json\/wp\/v2\/posts\/643\/revisions\/646"}],"wp:attachment":[{"href":"https:\/\/dadamo.com\/dangerous\/wp-json\/wp\/v2\/media?parent=643"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/dadamo.com\/dangerous\/wp-json\/wp\/v2\/categories?post=643"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/dadamo.com\/dangerous\/wp-json\/wp\/v2\/tags?post=643"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}