Dr. Peter D'Adamo/ The Blood Type Diets



DR. D'ADAMO: LECSTER 7


The lectin database of Dr. Peter D'Adamo.
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Cytisus scoparius

SPECIES IMAGE
SOURCEScotch broom
LECTINSCSA-I, CSA-II, CMH-I, CMH-II
MOLECULAR IMAGE
CLASS
NOMENLECp.Cyt.Sco.se.Hga1 (CS-I) LECp.Cyt.Sco.se.Hga2 (CS-II)
INDEXPlant lectin / Plant / Seed / Hololectins / Gal/GalNAc-binding lectins
CHARACTERIZATIONTwo anti-H(O) lectins were separated from extracts of Cytisus sessilifolius seeds by successive affinity chromatographies on columns of di-N-acetylchitobiose- and galactose-Sepharose 4B. One was found to be inhibited most by di-N-acetylchitotriose or tri-N-acetylchitotriose [Cytisus-type anti-H(O) lectin designated as Cytisus sessilifolius lectin I (CSA-I)] and the other anti-H(O) lectin was inhibited by galactose or lactose and designated as Cytisus sessilifolius lectin II (CSA-II).
BIOACTIVITYCSA-I and CSA-II agglutinate blood group H(O) erythrocytes, as does CMH-I. CMH-II is a non-blood group specificy hemagglutinin.
SOURCE TISSUESeed
SPECIFICITY
INHIBITORSCMH-I is inhibited by di- N-acetylchitobiose or tri- N-acetylchitotriose. Treatment of human O erythrocytes with a purified H-decomposing enzyme (alpha-L-fucosidase from Bacillus fulminans abolished the agglutinability of the cells with CMH-I. This indi
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