Dr. Peter D'Adamo/ The Blood Type Diets



DR. D'ADAMO: LECSTER 7


The lectin database of Dr. Peter D'Adamo.
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Datura stramonium

SPECIES IMAGE
SOURCEJimson weed, thorn apple
LECTINSDSA
MOLECULAR IMAGE
CLASSChitin-bindng lectins
NOMENLECp.Dat.Str.se.Hch1
INDEXPlant lectin / Plant / Seed / Hololectins / GlcNAc/(GlcNAc)-binding lectins
CHARACTERIZATIONDSA may have a role in cell-cell interactions. The Datura lectins resemble the chitin-binding lectins from Solanum and Lycopersicon.
BIOACTIVITYDSA is nonspecific in human erythrocyte ABO system. It agglutinates all human erythrocytes equally well. See: 1) The lectin also agglutinates Ehrlich ascites tumor cells and human erythrocytes. See: FEBS Letters 1981 (130); 149-152 DSA induces histamine release from rat peritoneal mast cells. See: General Pharm 1996 (27); 123-128 DSA exerts some anti-nutritive effects. See: Br J Nutrit 1993 (70); 313-321
SOURCE TISSUESeed
SPECIFICITYGlcNAc (oligomers)
INHIBITORSNot inhibited by simple sugars but is inhibited by a partial hydrolysate of chitin-containing mixture of polysaccharides from Aspergillus niger. The inhibitory effectivity of n-acetylglucosamine increases with chain length. See: Arch Biochem Biophys 1984
REFERENCESBiochim Biophys Acta 1978 Jan 25;532(1):92-7
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