Dr. Peter D'Adamo/ The Blood Type Diets



DR. D'ADAMO: LECSTER 7


The lectin database of Dr. Peter D'Adamo.
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Homo sapiens

SPECIES IMAGE
SOURCE
LECTINSMannose-Specific Endocytosis Receptor
MOLECULAR IMAGE
CLASS
NOMENLECh.Hom.Sap.xx.Xma1
INDEXLectin from humans / / / / Mannose-binding lectins
CHARACTERIZATIONA plasma-membrane receptor expressed by rabbit alveolar macrophages that recognizes glycoprotein ligands bearing terminal mannose, fucose or N-acetylglucosamine residues.that recognizes glycoprotein ligands bearing terminal mannose, fucose or N-acetylglucosamine residues.
BIOACTIVITY
SOURCE TISSUE
SPECIFICITYThe purified protein binds mannose-BSA (bovine serum albumin) with a dissociation constant of 1.9 X 10(-8) M.
INHIBITORSThe binding of 125I-mannose-BSA is inhibited by ligands bearing high-mannose oligosaccharides, such as mannan or beta-glucuronidase, as well as the monosaccharides mannose, fucose and N-acetylglucosamine. Galactose, galactosylated BSA, glucose and mannos
REFERENCESBiochem J 1987 Aug 1;245(3):705-11
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