Dr. Peter D'Adamo/ The Blood Type Diets



DR. D'ADAMO: LECSTER 7


The lectin database of Dr. Peter D'Adamo.
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Homo sapiens

SPECIES IMAGE
SOURCE
LECTINSThrombospondin
MOLECULAR IMAGE
CLASS
NOMENLECh.Hom.Sap.xx.Xxxx
INDEXLectin from humans / / / /
CHARACTERIZATIONThrombospondin (TSP) is a glycoprotein secreted from the alpha-granules of platelets upon activation. In the presence of divalent cations, the secreted protein binds to the surface of the activated platelets and is responsible for the endogenous lectin-like activity associated with activated platelets.
BIOACTIVITY
SOURCE TISSUE
SPECIFICITYBinding of TSP to the platelet surface requires interaction with other platelet surface components in addition to fibrinogen. The observation that fibrinogen only partially inhibits the TSP-mediated agglutination of fixed, activated platelets is consistent with this interpretation.
INHIBITORS
REFERENCESBiochemistry 1985 Jun 18;24(13):3128-34
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