| CHARACTERIZATION | Alpha5/beta1 is a receptor for fibronectin. It is expressed on Memory-T-cells, monocytes, platelets and fibroblasts. This integrin is also known as VLA-5 (very late activation antigen 5), FNR (fibronectin receptor), GPIc-IIa (glycoprotein Ic-IIa on platelets) and ECMRVI (extracellular matrix receptor VI). AlphaV/beta1 is a receptor for fibronectin. ntegrins alpha5beta1, alphavbeta1, and alphavbeta6 collaborate in squamous carcinoma cell spreading and migration on fibronectin. See: Exp Cell Res 2000 Feb 25;255(1):10-7 |