Dr. Peter D'Adamo/ The Blood Type Diets



DR. D'ADAMO: LECSTER 7


The lectin database of Dr. Peter D'Adamo.
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Homo sapiens

SPECIES IMAGE
SOURCE
LECTINSAlpha-6 / Beta-7 integrin
MOLECULAR IMAGE
CLASSIntegrin A (or I) domain
NOMENINTh.Hom.Sap.xx.Xxxx
INDEX / / / /
CHARACTERIZATIONThe alpha4/beta7 integrin is a receptor for MadCAM, fibronectin and VCAM-1. This integrin is only found leukocytes which are directed to the Peyer's Patches of the gut. MadCAM which is an addressin, is only found on Peyer's Patch Endothelium. The alpha4/beta7 integrin is also known as (LPAM-1). Data show that protein synthesis-dependent upregulation of the functional beta7 integrin occurs under conditions when beta4 and beta1 integrins are fully expressed, indicating a sequential appearance of specific adhesion molecules on differentiating eosinophil progenitors. See: Allergy 2000 Sep;55(9):865-72
BIOACTIVITY
SOURCE TISSUE
SPECIFICITY
INHIBITORS
REFERENCES
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