Dr. Peter D'Adamo/ The Blood Type Diets



DR. D'ADAMO: LECSTER 7


The lectin database of Dr. Peter D'Adamo.
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Homo sapiens

SPECIES IMAGE
SOURCE
LECTINSVascular Adhesion Molecule (VCAM-1
MOLECULAR IMAGE
CLASS
NOMENLECh.Xxx.Xxx.xx.Xxxx
INDEXLectin from humans / / / /
CHARACTERIZATIONVCAM-1 plays a central role in leukocyte recruitment in colitis and blockade of this adhesion molecule has higher therapeutic effect than immunoneutralization of ICAM-1 or MAdCAM-1 in this experimental model. Lab Invest 2000 Oct;80(10):1541-51 There was enhanced expression of E-selectin, CLA, LFA-1, ICAM-1, VLA-4, VCAM-1, and alphaEbeta7 in psoriatic lesions versus nonlesional skin. See: Lab Invest 2001 Mar;81(3):335-47
BIOACTIVITY
SOURCE TISSUE
SPECIFICITY
INHIBITORSVCAM-1 is significantly more efficient than MAdCAM-1 in supporting eosinophil rolling under conditions of flow. See: Blood 2000;95:592-601) Chronic administration of anti-VCAM-1 antibody, but not anti-ICAM-1 or anti-MAdCAM-1, resulted in significant atte
REFERENCES
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