Dr. Peter D'Adamo/ The Blood Type Diets



DR. D'ADAMO: LECSTER 7


The lectin database of Dr. Peter D'Adamo.
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Homo sapiens

SPECIES IMAGE
SOURCE
LECTINSP-Selectin
MOLECULAR IMAGE
CLASSSelectin
NOMENSELh.Xxx.Xxx.xx.Xxxx
INDEX / / / /
CHARACTERIZATIONP-selectin and E-selectin expression were markedly up-regulated in colitic rats. P-selectin plays a key role on leukocyte rolling and its blockade attenuates leukocyte adhesion in TNBS-induced colitis. See: Gastroenterology 2001 Apr;120(5):1162-72 P-selectin is up-regulated following irradiation and is a key molecular determinant of leukocyte rolling but not leukocyte adhesion in this inflammatory condition. See:Int J Cancer 2001 Apr 20;96(2):99-109
BIOACTIVITY
SOURCE TISSUE
SPECIFICITY
INHIBITORSHuman P-selectin, ICAM-1 and VAP-1 appear to be the most promising targets when antiadhesive interventions preventing leukocyte-mediated tissue destruction after myocardial ischemia. See: J Am Coll Cardiol 2000 Jul;36(1):122-9
REFERENCES
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