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DR. D'ADAMO: LECSTER 7The lectin database of Dr. Peter D'Adamo. BACK TO INDEX | LECSTER7 FAQ |
Homo sapiens | |
| SPECIES IMAGE |  | SOURCE |
| LECTINS | Intercellular Adhesion Molecule (ICAM-1, ICAM-2) |
| MOLECULAR IMAGE |  | CLASS | Addressin? |
| NOMEN | LECh.Xxx.Xxx.xx.Xxxx |
| INDEX | Lectin from humans / / / / |
| CHARACTERIZATION | There was enhanced expression of E-selectin, CLA, LFA-1, ICAM-1, VLA-4, VCAM-1, and alphaEbeta7 in psoriatic lesions versus nonlesional skin. See: Lab Invest 2001 Mar;81(3):335-47 |
| BIOACTIVITY | |
| SOURCE TISSUE | |
| SPECIFICITY | |
| INHIBITORS | Human P-selectin, ICAM-1 and VAP-1 appear to be the most promising targets when antiadhesive interventions preventing leukocyte-mediated tissue destruction after myocardial ischemia. See: J Am Coll Cardiol 2000 Jul;36(1):122-9 |
| REFERENCES | |
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