Dr. Peter D'Adamo/ The Blood Type Diets



DR. D'ADAMO: LECSTER 7


The lectin database of Dr. Peter D'Adamo.
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Homo sapiens

SPECIES IMAGE
SOURCE
LECTINSActivated Leukocyte Adhesion Molecule (ALCAM)
MOLECULAR IMAGE
CLASS
NOMENLECh.Hom.Sapxx
INDEXLectin from humans / / / /
CHARACTERIZATIONCD6 and its ligand activated leukocyte cell adhesion molecule (ALCAM, CD166) have been detected on various immune cells and in the brain. CD6-ligand interactions have been implicated in the regulation of T cell function. See: Protein Sci 1997 Aug;6(8):1768-70 CD6-ligand interactions have been implicated in the regulation of T-cell adhesion and activation. CD6 is a member of the scavenger receptor family, whereas its human ligand (ALCAM) belongs to the immunoglobulin superfamily. The extracellular region of ALCAM includes five immunoglobulin-like domains. As a fusion protein, the N-terminal extracellular domain of ALCAM (ALCAMD1) binds specifically to CD6. See: Protein Sci 1995 Aug;4(8):1644-7
BIOACTIVITYActivated leukocyte cell adhesion molecule (ALCAM) and annexin II are involved in the metastatic progression of tumor cells after chemotherapy with Adriamycin. See: Clin Exp Metastasis 2000;18(1):45-50
SOURCE TISSUE
SPECIFICITY
INHIBITORS
REFERENCES
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