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DR. D'ADAMO: LECSTER 7The lectin database of Dr. Peter D'Adamo. BACK TO INDEX | LECSTER7 FAQ |
Homo sapiens | |
| SPECIES IMAGE | ![]() | SOURCE |
| LECTINS | E-cadherin |
| MOLECULAR IMAGE | ![]() | CLASS |
| NOMEN | CDHh.Hom.Sap.xx.XxxE |
| INDEX | / / / / |
| CHARACTERIZATION | E-cadherin, a calcium-dependent transmembrane glycoprotein, is an adhesion molecule. The loss of E-cadherin expression may be involved in regional lymph node metastasis and in malignant potential of thyroid neoplasms. See:J Surg Oncol 2001 Mar;76(3):176-80 For role of P and E-cadherins in metastasis, See:Mod Pathol 2001 May;14(5):423-7 There are higher levels of soluble E-cadherin in cyst fluid from malignant ovarian tumours than in benign cysts. See: Anticancer Res. 2001 Jan-Feb;21(1A):65-70. |
| BIOACTIVITY | |
| SOURCE TISSUE | |
| SPECIFICITY | |
| INHIBITORS | |
| REFERENCES | Annu Rev Biochem 1990;59:237-52 |
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