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DR. D'ADAMO: LECSTER 7The lectin database of Dr. Peter D'Adamo. BACK TO INDEX | LECSTER7 FAQ |
Lotus tetragonolobus | |
| SPECIES IMAGE | ![]() | SOURCE | Aparagus pea |
| LECTINS | LTA |
| MOLECULAR IMAGE | ![]() | CLASS | Legume lectins |
| NOMEN | LECp.Lot.Tet.se.Hfu1 |
| INDEX | Plant lectin / Plant / Seed / Hololectins / Fucose-binding lectins |
| CHARACTERIZATION | LTA is a metalloprotein that is a mixture of isolectins which are glycosylated. See: carbohydrate Res 1977 (58); 253-265 Separation of the lectin components by DEAE cellulose chromatography yielded two major fractions: a potent hemagglutinin with weak macrophage activating properties and a potent macrophage activator with weak hemagglutinating activity. See: Immunobiology 1985 Apr;169(3):250-62 |
| BIOACTIVITY | LTA is specific for human blood group H(O). See: Nature 1967 (215); 890-891 |
| SOURCE TISSUE | Seed |
| SPECIFICITY | Fuc (alpha-L-Fuc; blood group H/o) |
| INHIBITORS | Its agglutination was most inhibited by L-fucose See: Nature 1967 (215); 890-891 and Biochemistry 1974 (13); 3184-3192 |
| REFERENCES | J Chromatogr 1992 Apr 24;597(1-2):213-9 |
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