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DR. D'ADAMO: LECSTER 7The lectin database of Dr. Peter D'Adamo. BACK TO INDEX | LECSTER7 FAQ |
Anguilla anguilla | |
| SPECIES IMAGE | ![]() | SOURCE | Fresh water eel |
| LECTINS | AAL |
| MOLECULAR IMAGE | ![]() | CLASS |
| NOMEN | LECi.Ang.Ang.xx.Xfu1 |
| INDEX | Lectin from invertebrates / / / / Fucose-binding lectins |
| CHARACTERIZATION | In immunohistochemical studies, the reactivity of AAA and UEA-I in normal pyloric mucosa from individuals with known Lewis and secretor status was analysed. AAA showed a broad reaction in the superficial pyloric mucosa from secretors and non-secretors, but AAA reactivity was more pronounced in Le(a+b-) individuals. On the other hand, UEA-I stained the superficial pyloric mucosa only from secretor individuals. |
| BIOACTIVITY | H(O) blood group |
| SOURCE TISSUE | |
| SPECIFICITY | alpha-L-Fuc |
| INHIBITORS | alpha-L-Fuc; Binding of AAL to gastric mucin was competitively neutralized by Le(a)-specific monoclonal antibodies. |
| REFERENCES | J. Biochim. Biophys. Acta, 538, 299, (1984) Glycoconj J 1996 Aug;13(4):585-90 |
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