Pleurotus ostreatus |
| SPECIES IMAGE |  |
SOURCE | Oyster mushroom |
| LECTINS | |
| MOLECULAR IMAGE |  |
CLASS | |
| NOMEN | LECf.Ple.Ost.xx.Xxxx |
| INDEX | Lectin from fungi / / / / |
| CHARACTERIZATION | The mycelial lectin appeared prior to fruit body formation and disappeared during the formation of fruit bodies. The lectin was localized on the surface of solid-medium-grown mycelia, and only dikaryotic, and not monokaryotic, mycelia produced the lectin. These results suggest that the appearance of this lectin is associated with fruit body formation. The lectin exerted potent antitumor activity in mice bearing sarcoma S-180 and hepatoma H-22. Survival in these mice was prolonged and body weight increase reduced after lectin treatment. See:Biochem Biophys Res Commun 2000 Sep 7;275(3):810-6 |
| BIOACTIVITY | |
| SOURCE TISSUE | |
| SPECIFICITY | |
| INHIBITORS | Hemagglutinating activity of this lectin was completely inhibited by 2-mercaptoethanol, indicating that the multimer is active. Its hemagglutinating activity was sensitive to inhibition by CaCl(2), MgCl(2), MnCL(2) and FeCl(3) and potentiation by AlCl(3) |
| REFERENCES | Plant Sci 2001 Apr;160(5):1025-1033 for Pleurotus cornucopiae see: J Bacteriol 1996 Oct;178(19):5692-8 |