DR. D'ADAMO: LECSTER 7

The lectin database of Dr. Peter D'Adamo.
BACK TO INDEX | LECSTER7 FAQ

Aplysia dactylomela
SPECIES IMAGE
SOURCE	Sea hare shrimp
LECTINS
MOLECULAR IMAGE
CLASS
NOMEN	LECi.Apl.Dac.xx.Xxxx
INDEX	Lectin from invertebrates / / / /
CHARACTERIZATION
BIOACTIVITY	The fluid preferentially agglutinated rabbit erythrocytes and, to a lesser extent, human blood cells, and this activity was inhibited by the glycoprotein fetuin. Aplysia gonad lectin, like human anti-I, strongly agglutinates and adsorbs to adult I-positive red cells, differentiating between them and fetal or rare I-negative adult red cells (although with less of a difference). In contrast to the plant and microbial lectins examined, its I-affinity does not depend on the presence of ABH or P system antigens and it clearly detects higher I antigen expression in O(h) red cells. The hemagglutinating activity of Aplysia lectin as that of all the I-detecting proteins is enhanced at 4 degrees C, but unlike the human anti-I Aplysia lectin-induced hemagglutination is stable at room temperature. See: Transfusion 1999 Oct;39(10):1060-4
SOURCE TISSUE
SPECIFICITY
INHIBITORS
REFERENCES	Braz J Med Biol Res 1998 Jun;31(6):785-91