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DR. D'ADAMO: LECSTER 7The lectin database of Dr. Peter D'Adamo. BACK TO INDEX | LECSTER7 FAQ |
Ulex europaeus | |
| SPECIES IMAGE | ![]() | SOURCE | Gorse seed |
| LECTINS | UEA-I, UEA-II, UEA-III |
| MOLECULAR IMAGE | ![]() | CLASS | Legume lectin |
| NOMEN | LECp.Ule.Eur.xx.Xxxx |
| INDEX | Plant lectin / / / / |
| CHARACTERIZATION | Lipsomal preparations ofUEA have potential as oral vaccine carriers. In mice 10.5% of the total dose of WGA liposomes were taken up from the gastrointestinal tract. See: Pharm Res 1996 Sep;13(9):1378-83 |
| BIOACTIVITY | UEA-I agglutinatesblood group H(O). However, shown to aggltuinate human group A erythrocytes at a titer of 1:32; group B erythrocytes at a titer of 1:16; group B erythrocytes at a titer of 1:16; by crude lectin preparation (16mg/ml). See: Int J Cancer 1970;6:283 |
| SOURCE TISSUE | |
| SPECIFICITY | L-fucose (UEA-I); di-N-acetylchitobiose (UEA-II) |
| INHIBITORS | For characterization of UEA-II, see: Hoppe Seylers Z Physiol Chem. 1981 Jul;362(7):983-9. UEA-III was found to be inhibited by lactose. (Biol Chem Hoppe Seyler 1991 Feb;372(2):95-102) |
| REFERENCES | Glycoconj J 1996 Aug;13(4):585-90 J Chromatogr 1992 Apr 24;597(1-2):213-9 |
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