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Questions About The Diets

Type B, Non-Secretors and Bladder Infection


I'm a type B who has always been challenged by recurring bladder infections -since early childhood. Is there any herbs or food I can take to help minimize the almost non-stop use of antibiotics?


The bladder wall is open of the tissues most heavily deposited with ABO blood group antigens. As a matter of fact, it is known well accepted that the loss of blood group antigens from the bladder wall is almost always associated with malignancy

ABO blood groups and cancer have an interesting relationship; in tissues not normally though to contain much blood type antigen, such as the thyroid, malignancy often is hallmarked with the inappropriate elaboration of blood type antigen. In tissues that normally contain ABO antigens, malignancy is often preceded by the loss of blood group antigens.

Urinary tract infections have been associated with ABO blood group, especially with group B (1), although other studies have disputed this. (2) What is not disputed, however, is the link between recurrent bladder infections and an increased incidence of chronic inflammation, with ABH non-secretors (3,4,5,6) When ABO blood group is factored with secretor status, the association becomes much stronger: Group B non-secretors have a much higher rate of chronic urinary tract infection and scarring over other blood groups. (7)

What to do:

The most basic strategy is to 1)find out if you are a non-secretor, 2.) if you are, to use a product like Deflect to provide blood type polysaccharides to in effect mimic the effect of being a secretor.

Non-secretors are more prone to infection because their inability to secrete their ABO blood type antigen in a 'free form' in such tissues as mucus and saliva deprives them of a way to inhibit bacteria from attaching to their tissue membranes. Think of bacteria as a piece of scotch tape. Now imagine the bladder wall as a piece of paper. Then imagine the bladder wall of a secretor being dusted with talcum powder. The scotch tape cannot attach to the bladder wall (paper) because the receptors were flooded by free blood type antigen (talc). A non-secretor has only the paper (no talc; i.e. no free blood type antigen) so the scotch tape (bacteria) can attach very easily.

Non-secretors will want to use a product like Deflect since it provides the 'talc' that they genetically cannot manufacture themselves.

2.Hopkins WJ, Heisey DM, Lorentzen DF, Uehling DT. A comparative study of major histocompatibility complex and red blood cell antigen phenotypes as risk factors for recurrent urinary tract infections in women.

3. Jantausch BA, Criss VR, O'Donnell R, Wiedermann BL, Majd M, Rushton HG, Shirey RS, Luban NL. Association of Lewis blood group phenotypes with urinary tract infection in children. J Pediatr. 1994 Jun;124(6):863-8.

4.Lomberg H, Jodal U, Leffler H, De Man P, Svanborg C. Blood group non-secretors have an increased inflammatory response to urinary tract infection. Scand J Infect Dis. 1992;24(1):77-83

5.Lomberg H, Jodal U, Leffler H, De Man P, Svanborg C. Blood group non-secretors have an increased inflammatory response to urinary tract infection. Scand J Infect Dis. 1992;24(1):77-83.

6. May SJ, Blackwell CC, Brettle RP, MacCallum CJ, Weir DM. Non-secretion of ABO blood group antigens: a host factor predisposing to recurrent urinary tract infections and renal scarring. FEMS Microbiol Immunol. 1989 Jun;1(6-7):383-7.

7. Ratner JJ, Thomas VL, Forland M. Relationships between human blood groups, bacterial pathogens, and urinary tract infections. Am J Med Sci. 1986 Aug;292(2):87-91.

The Ask Dr. D'Adamo internet advice column ran from 1996 to 2009, at which time Dr. D'Adamo's teaching and programming responsibilities no longer allowed him to devote time and resources to directly answering visitor questions. However we've recently reorganized this treasure-trove of material and made it again available to his readership. He occasionally posts new entries. These are marked with a NEW tag.

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