I’ve been building a database of potential agents (drugs, botanical, supplements and foods) that have some evidence basis behind their use as antivirals against the novel coronavirus. The online database can be accessed here.
CoVD2019: 02/09/2020 And in today’s bad news. ‘Initially, the basic reproductive number, R0, was estimated to be 2.2 to 2.7. Here we provide a new estimate of this quantity… Integrating these estimates and high-resolution real-time human travel and infection data with mathematical models, we estimated that the number of infected individuals during early epidemic double
A nightmare scenario and a nothing-burger are just two possible Wuhan Coronavirus outcomes, and there’s a whole lot gray area in-between. This post is what I have been thinking about the last day or two. Keep in mind these are just my opinions and observations over a thin veneer of facts. And not much more.
Mannose-binding lectins are inhibitors of SARS-like coronaviruses. Best food sources of mannose-binding lectins? Monocots, such as leeks, garlic and onions. Fresh crushed garlic probably best. Mannose binding lectin (MBL) is also made internally via the MBL2 gene as part of the body’s immune complement system. Low levels of MBL are well-associated with immune compromise, most
Wuhan Coronavirus (1/25/2020) Due to the latency of the virus, the effects of the current active public health measures underway, media fatigue, and the extensive (and largely terrible) coverage in the media, an inevitable (and understandable) backlash is the invariable result. Overly facile responses to what some consider ‘coronavirus hype’ often feature irresponsible comparisons of
Some pretty pictures of detoxification network analysis courtesy of an app I’m developing called ‘Rheingold,’ which takes drug/ supplement/ food queries and returns predicted cytochrome consequences. In addition, with this client I was able to superimpose their Opus23 genomic data, and as can be seen in the image, the red box for CYP2D6 shows a
The Dunning-Kruger effect is a type of cognitive bias in which people believe that they are smarter and more capable than they really are. In a nutshell, ignorant people do not possess the skills needed to recognize their own incompetence. In other words, you have to be somewhat intelligent in order to realize just how
I’ve been exploring artificial intelligence (AI) modules from the Comprehensive Perl Archive Network (CPAN), a great resource for legally stealing very useful tools made by people far smarter than me. One of their featured machine learning modules is also one of the simplest. It’s called the ‘Naive Bayes’ algorithm. I like simple, so I started
The UB/COEGM Pathfinder Scholarship Program is a partnership between the University of Bridgeport School of Health Sciences and the Center of Excellence in Generative Medicine. Its mission is to groom developing physicians in the skills of twenty-first century precision medicine through the use of bioinformatics. It’s been my honor and privilege to act as a
When an old colleague alerted me that Dr. Alan Gaby had written an editorial (Townsend Letter, September 2018) critical of my theories regarding the use of ABO expression in the gut as a potential indicator of certain dietary relationships, I was of course quite concerned. Dr. Gaby is a well-regarded authority on nutritional science, and
Studies are increasingly indicating that almost any change you make to the diet changes your gut microbiota. Those changes might be slight, and in fact difficult to predict from person to person, but they are there. Now new research seems to indicate that eating white button mushrooms daily can act as a prebiotic by improving
‘People don’t have ideas, ideas have people.’ —Carl Jung Science Based Medicine (SBM), the self-styled parser of all that is untrue, fraudulent, and unbelievable in modern clinical medicine, has a long history of trashing medical theories and methods that don’t fit their particular standards for ‘evidence.’ It’s a breathtakingly ambitious title for a website, since
When writing the revised edition of Eat Right For Your Type, I alluded to the difficulties of doing nutritional and dietary research, and used salt as a prime example. It has been suggested that a statistically significant, well-powered study on the health effects of salt would have to enroll 28,000 patients for at least five
Trehalose is a sugar consisting of two molecules of glucose. However unlike the sugar on top of a jelly doughnut, it does not display the qualities of glucose when introduced into the body as it resists breakdown back into the simple sugars. Trehalose has high water retention capabilities, and is used in food, cosmetics, and
What does an extension cord, a trip to Disneyland, and serving of spinach have in common? Apparently, they can give you cancer. At least in California. California’s Proposition 65, also called the Safe Drinking Water and Toxic Enforcement Act, was enacted in 1986. It is intended to help Californians make informed decisions about protecting themselves