Genus
and species
This is the standard scientific nomenclature,
in Latin.
Common nomenclature
Although
considered archaic, trivial names and three letter abbreviations
constitute the most common way many lectin are represented in the literature.
Source organism
This
is most usually whatever common name the source of the lectin or galectin is
known by, if any.
Source tissue
This
is most usually where the lectin has been isolated. They are identified in table
3.
Specificity
The
overall specificity of the lectin or galectin. When the specificity has been
determined in detail, the most inhibitory compound is indicated in brackets.
Inhibitors
What
glycoconjugates have been shown to inhibit biological activity (most usually
hemagglutination.)
Biologic activity
What
biologic systems have been shown to be influenced by the lectin, with relevant
literature references. These are most often hemagglutination or mitogenic
reactions. ABO or other blood group specificity provided when possible.
References
References
which can be consider authoritative as far as characterization of the lectin is
concerned.
Characterization notes
Structure/
function reports with relevant literature citations
Lectin nomenclature
Lecster uses an expanded lectin nomenclature
system originally proposed for plant lectins by Van Damme et al (Handbook of
Plant Lectins, John Wiley & Sons). This allows
a more specific identification of the lectin and carries with it the added
benefit of much relevant information being contained directly in the key. Also,
once comprehended, it becomes perhaps the most sophisticated way to search
Lecster via partial entries.
It takes the following form:
An explanation of each index variable follows.
LLL refers to the general category of agglutinin. At this point six general categories are recognized: lectins (LEC), integrins (INT), cadherins (CDH), annexins (ANN), selectins (SEL) and galectins (GLT). The x value refers to the taxonomic groups of the agglutinin, Table 1 summarizes these categories:
| Category | Taxonomic group |
| LECa, GLTa | Lectin or galectin from higher animal, typically vertebrates. |
| LECh, GLTh | Lectin or galectin from humans |
| LECi, GLTi | Lectin or galectin from invertebrates |
| LECp. | Plant lectins |
| LECf. | Lectin from fungi |
| LECu. | Lectin from unicellular organisms |
| LECb. | Lectin from Bacteria |
| LECv. | Viral lectins |
Ggg stands for the three first letters of the plant genus name (in Latin).
Sss stands for the three first letters of the plant species name (in Latin).
ti refers to the tissue from which the lectin has been isolated. Table
2
summarizes the indices used for the various tissues.
| Tissue,cell or organ | Taxonomic grouping | Index |
| Bark | Plant | ba |
| Bulb | Plant | bu |
| Cell membrane | Bacteria, Unicellular | cm |
| Epidermis | Human, vertebrates | ep |
| Fruit | Plant | fr |
| Hemolymph | Invertebrates | he |
| Latex | Plant | la |
| Leaf | Plant | le |
| Nodule | Plant | no |
| Organ or cell type | Human, vertebrates, Invertebrates | oc |
| Phloem sap | Plant | ps |
| Rhizome | Plant | rh |
| Root | Plant | ro |
| Seed | Plant | se |
| Serum or plasma | Human, vertebrates, Invertebrates | sr |
| Spores or fruiting bodies | Fungi | sp |
| Stem | Plant | st |
| Tentacles | Invertebrates | te |
| Tuber | Plant | tu |
| Whole body homogenate | Invertebrates | wb |
| Venom | Invertebrates | ve |
| Undefined | Human, vertebrates, Invertebrates, Bacteria, Unicellular, Virus, Fungal | un |
T refers to the lectin subtype. Hololectins, merolectins, chimerolectins and superlectins are indicated by the letters H, M, C and S, respectively.
sp refers to the specificity group. Each group is indicated by the index given in Table
3
| Specificity | Index of group |
| Mannose-binding lectins | ma |
| Mannose/maltose-binding lectins | mm |
| Mannose/glucose-binding lectins | mg |
| GlcNAc/(GlcNAc)-binding lectins | ch |
| Gal/GalNAc-binding lectins | ga |
| Fucose-binding lectins | fu |
| Sialic acid-binding lectins | si |
| Lectins with a complex but known specificity | co |
| Lectins with a complex and unknown specificity | cu |
| Lectins with a dual specificity | du |
| Lectins with an undetermined specificity | nd |
N is used to distinguish different lectins of the same specificity group which may occur in the same tissue of a single plant species. When a plant contains only one lectin of a given specificity in a particular tissue, the number is 1. In case different lectins of the same specificity are found in the same tissue, numbers refer to the (chronological) order of their discovery.
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